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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 6-phospho-1-fructokinase | ||
| Ligand | BDBM50446093 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1288121 | ||
| IC50 | 1460±n/a nM | ||
| Citation |  Brimacombe KR; Walsh MJ; Liu L; Vásquez-Valdivieso MG; Morgan HP; McNae I; Fothergill-Gilmore LA; Michels PA; Auld DS; Simeonov A; Walkinshaw MD; Shen M; Boxer MB Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase. ACS Med Chem Lett 5:12-7 (2014) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 6-phospho-1-fructokinase | |||
| Name: | 6-phospho-1-fructokinase | ||
| Synonyms: | n/a | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 53537.94 | ||
| Organism: | Trypanosoma brucei | ||
| Description: | ChEMBL_1288121 | ||
| Residue: | 487 | ||
| Sequence: |
| ||
| BDBM50446093 | |||
| n/a | |||
| Name | BDBM50446093 | ||
| Synonyms: | CHEMBL3108865 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H16Cl2N2O4S | ||
| Mol. Mass. | 451.323 | ||
| SMILES | Oc1cccc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(Cl)c3)cc2)c1 | ||
| Structure | 
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