| Reaction Details |
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 | Report a problem with these data |
| Target | Oxoeicosanoid receptor 1 |
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| Ligand | BDBM50446953 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1290750 (CHEMBL3117762) |
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| IC50 | 402±n/a nM |
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| Citation |  Gore, V; Gravel, S; Cossette, C; Patel, P; Chourey, S; Ye, Q; Rokach, J; Powell, WS Inhibition of 5-oxo-6,8,11,14-eicosatetraenoic acid-induced activation of neutrophils and eosinophils by novel indole OXE receptor antagonists. J Med Chem57:364-77 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxoeicosanoid receptor 1 |
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| Name: | Oxoeicosanoid receptor 1 |
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| Synonyms: | 5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | OXER1_HUMAN | Oxoeicosanoid receptor 1 | TG 1019 | TG1019 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45833.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | TG 1019 0 HUMAN::Q8TDS5 |
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| Residue: | 423 |
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| Sequence: | MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPS
FSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIH
TRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASV
VFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSY
RVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMV
VAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSP
NFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGS
SQG
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| BDBM50446953 |
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| n/a |
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| Name | BDBM50446953 |
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| Synonyms: | CHEMBL3115774 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H26ClNO3 |
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| Mol. Mass. | 363.878 |
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| SMILES | CCCCCCc1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O |
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| Structure | 
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