| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oxoeicosanoid receptor 1 |
|---|
| Ligand | BDBM50446961 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1290942 (CHEMBL3118915) |
|---|
| IC50 | 30±n/a nM |
|---|
| Citation |  Gore, V; Gravel, S; Cossette, C; Patel, P; Chourey, S; Ye, Q; Rokach, J; Powell, WS Inhibition of 5-oxo-6,8,11,14-eicosatetraenoic acid-induced activation of neutrophils and eosinophils by novel indole OXE receptor antagonists. J Med Chem57:364-77 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Oxoeicosanoid receptor 1 |
|---|
| Name: | Oxoeicosanoid receptor 1 |
|---|
| Synonyms: | 5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | OXER1_HUMAN | Oxoeicosanoid receptor 1 | TG 1019 | TG1019 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 45833.20 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | TG 1019 0 HUMAN::Q8TDS5 |
|---|
| Residue: | 423 |
|---|
| Sequence: | MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPS
FSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIH
TRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASV
VFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSY
RVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMV
VAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSP
NFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGS
SQG
|
|
|
|---|
| BDBM50446961 |
|---|
| n/a |
|---|
| Name | BDBM50446961 |
|---|
| Synonyms: | CHEMBL3115786 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H26BrNO3 |
|---|
| Mol. Mass. | 408.329 |
|---|
| SMILES | CCCCCCc1cc2ccc(Br)cc2n1C(=O)CC(C)CC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
