| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphatidylcholine:ceramide cholinephosphotransferase 2 |
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| Ligand | BDBM50447013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1289164 (CHEMBL3119037) |
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| IC50 | 75000±n/a nM |
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| Citation |  Deng, X; Lin, F; Zhang, Y; Li, Y; Zhou, L; Lou, B; Li, Y; Dong, J; Ding, T; Jiang, X; Wang, R; Ye, D Identification of small molecule sphingomyelin synthase inhibitors. Eur J Med Chem73:1-7 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphatidylcholine:ceramide cholinephosphotransferase 2 |
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| Name: | Phosphatidylcholine:ceramide cholinephosphotransferase 2 |
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| Synonyms: | SGMS2 | SMS2 | SMS2_HUMAN | Sphingomyelin synthase 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42294.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108027 |
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| Residue: | 365 |
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| Sequence: | MDIIETAKLEEHLENQPSDPTNTYARPAEPVEEENKNGNGKPKSLSSGLRKGTKKYPDYI
QIAMPTESRNKFPLEWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDY
IDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFCFIIGTLYLYRCITMYVTTLP
VPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVTLTLTYLFI
KEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTIDVIIAYYITTRLFWWYHSMANEKNL
KVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGED
NEKST
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| BDBM50447013 |
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| n/a |
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| Name | BDBM50447013 |
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| Synonyms: | CHEMBL3116074 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H16N2O2 |
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| Mol. Mass. | 328.3639 |
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| SMILES | Oc1ccccc1C1Oc2ccccc2C(C#N)N1c1ccccc1 |
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| Structure | 
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