| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein-arginine deiminase type-1 |
|---|
| Ligand | BDBM50447757 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1290380 (CHEMBL3119095) |
|---|
| IC50 | 950±n/a nM |
|---|
| Citation |  Dreyton, CJ; Anderson, ED; Subramanian, V; Boger, DL; Thompson, PR Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation. Bioorg Med Chem22:1362-9 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein-arginine deiminase type-1 |
|---|
| Name: | Protein-arginine deiminase type-1 |
|---|
| Synonyms: | PAD1 | PADI1 | PADI1_HUMAN | PDI1 | Peptidylarginine deiminase I | Protein-arginine deiminase type I |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 74664.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1290380 |
|---|
| Residue: | 663 |
|---|
| Sequence: | MAPKRVVQLSLKMPTHAVCVVGVEAHVDIHSDVPKGANSFRVSGSSGVEVFMVYNRTRVK
EPIGKARWPLDTDADMVVSVGTASKELKDFKVRVSYFGEQEDQALGRSVLYLTGVDISLE
VDTGRTGKVKRSQGDKKTWRWGPEGYGAILLVNCDRDNHRSAEPDLTHSWLMSLADLQDM
SPMLLSCNGPDKLFDSHKLVLNVPFSDSKRVRVFCARGGNSLSDYKQVLGPQCLSYEVER
QPGEQEIKFYVEGLTFPDADFLGLVSLSVSLVDPGTLPEVTLFTDTVGFRMAPWIMTPNT
QPPEELYVCRVMDTHGSNEKFLEDMSYLTLKANCKLTICPQVENRNDRWIQDEMEFGYIE
APHKSFPVVFDSPRNRGLKDFPYKRILGPDFGYVTREIPLPGPSSLDSFGNLDVSPPVTV
GGTEYPLGRILIGSSFPKSGGRQMARAVRNFLKAQQVQAPVELYSDWLSVGHVDEFLTFV
PTSDQKGFRLLLASPSACLKLFQEKKEEGYGEAAQFDGLKHQAKRSINEMLADRHLQRDN
LHAQKCIDWNRNVLKRELGLAESDIVDIPQLFFLKNFYAEAFFPDMVNMVVLGKYLGIPK
PYGPIINGRCCLEEKVQSLLEPLGLHCIFIDDYLSYHELQGEIHCGTNVRRKPFPFKWWN
MVP
|
|
|
|---|
| BDBM50447757 |
|---|
| n/a |
|---|
| Name | BDBM50447757 |
|---|
| Synonyms: | CHEMBL57818 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H9N3O2 |
|---|
| Mol. Mass. | 251.2402 |
|---|
| SMILES | NC1=CC(=O)c2ccc(nc2C1=O)-c1ccccn1 |t:1| |
|---|
| Structure | 
|
|---|
Search and Browse
