Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Acetylcholine receptor subunit epsilon | ||
| Ligand | BDBM50448371 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1292388 (CHEMBL3123981) | ||
| IC50 | 22909±n/a nM | ||
| Citation |  Matera, C; Flammini, L; Quadri, M; Vivo, V; Ballabeni, V; Holzgrabe, U; Mohr, K; De Amici, M; Barocelli, E; Bertoni, S; Dallanoce, C Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity. Eur J Med Chem75:222-32 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Acetylcholine receptor subunit epsilon | |||
| Name: | Acetylcholine receptor subunit epsilon | ||
| Synonyms: | ACHE_RAT | Acetylcholine receptor protein epsilon chain | Achre | Chrne | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 54930.09 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_1292388 | ||
| Residue: | 494 | ||
| Sequence: |
| ||
| BDBM50448371 | |||
| n/a | |||
| Name | BDBM50448371 | ||
| Synonyms: | CHEMBL3121480 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C33H44N4O4 | ||
| Mol. Mass. | 560.7258 | ||
| SMILES | C[N+](C)(CCCCCC[N+]1(C)CCC(CC1)N1C(=O)c2cccc3cccc(C1=O)c23)CC#CCOC1=NOCC1 |t:40,(26.01,-22.81,;26.76,-24.15,;27.54,-22.83,;25.23,-24.16,;24.45,-22.84,;22.91,-22.84,;22.13,-21.52,;20.59,-21.53,;19.81,-20.19,;18.27,-20.2,;19.03,-18.86,;17.49,-18.87,;15.95,-18.88,;15.19,-20.22,;15.97,-21.55,;17.51,-21.54,;13.65,-20.23,;12.88,-18.89,;13.64,-17.57,;11.35,-18.91,;10.58,-17.58,;9.05,-17.57,;8.28,-18.91,;9.04,-20.25,;8.28,-21.58,;9.06,-22.91,;10.59,-22.9,;11.35,-21.57,;12.9,-21.56,;13.67,-22.88,;10.58,-20.24,;27.53,-25.5,;29.07,-25.51,;30.61,-25.5,;32.15,-25.5,;32.92,-26.83,;34.46,-26.82,;35.38,-28.05,;36.84,-27.57,;36.83,-26.03,;35.37,-25.56,)| | ||
| Structure | 
| ||