| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 11 |
|---|
| Ligand | BDBM50293361 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1335261 (CHEMBL3238614) |
|---|
| IC50 | 73000±n/a nM |
|---|
| Citation |  Cincinelli, R; Musso, L; Giannini, G; Zuco, V; De Cesare, M; Zunino, F; Dallavalle, S Influence of the adamantyl moiety on the activity of biphenylacrylohydroxamic acid-based HDAC inhibitors. Eur J Med Chem79:251-9 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 11 |
|---|
| Name: | Histone deacetylase 11 |
|---|
| Synonyms: | HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11 |
|---|
| Type: | Chromatin regulator; hydrolase; repressor |
|---|
| Mol. Mass.: | 39187.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q96DB2 |
|---|
| Residue: | 347 |
|---|
| Sequence: | MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
|
|
|
|---|
| BDBM50293361 |
|---|
| n/a |
|---|
| Name | BDBM50293361 |
|---|
| Synonyms: | CHEMBL561209 | N-Hydroxy-E-3-(4'-methoxybiphenyl-4-yl)-acrylamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H15NO3 |
|---|
| Mol. Mass. | 269.2952 |
|---|
| SMILES | COc1ccc(cc1)-c1ccc(\C=C\C(=O)NO)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
