| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase 20 |
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| Ligand | BDBM50007790 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1335827 (CHEMBL3239936) |
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| IC50 | >100000±n/a nM |
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| Citation |  Báez-Santos, YM; Barraza, SJ; Wilson, MW; Agius, MP; Mielech, AM; Davis, NM; Baker, SC; Larsen, SD; Mesecar, AD X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases. J Med Chem57:2393-412 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ubiquitin carboxyl-terminal hydrolase 20 |
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| Name: | Ubiquitin carboxyl-terminal hydrolase 20 |
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| Synonyms: | Deubiquitinating enzyme 20 | KIAA1003 | LSFR3A | UBP20_HUMAN | USP20 | Ubiquitin thioesterase 20 | Ubiquitin-specific-processing protease 20 | VDU2 | VHL-interacting deubiquitinating enzyme 2 | hVDU2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 101993.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108270 |
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| Residue: | 914 |
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| Sequence: | MGDSRDLCPHLDSIGEVTKEDLLLKSKGTCQSCGVTGPNLWACLQVACPYVGCGESFADH
STIHAQAKKHNLTVNLTTFRLWCYACEKEVFLEQRLAAPLLGSSSKFSEQDSPPPSHPLK
AVPIAVADEGESESEDDDLKPRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLV
RTDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLM
DQLHEELKEPVVATVALTEARDSDSSDTDEKREGDRSPSEDEFLSCDSSSDRGEGDGQGR
GGGSSQAETELLIPDEAGRAISEKERMKDRKFSWGQQRTNSEQVDEDADVDTAMAALDDQ
PAEAQPPSPRSSSPCRTPEPDNDAHLRSSSRPCSPVHHHEGHAKLSSSPPRASPVRMAPS
YVLKKAQVLSAGSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIP
GKEDLAKLHSAIYQNVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTLE
DCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKIN
SHVSFPLEGLDLRPFLAKECTSQITTYDLLSVICHHGTAGSGHYIAYCQNVINGQWYEFD
DQYVTEVHETVVQNAEGYVLFYRKSSEEAMRERQQVVSLAAMREPSLLRFYVSREWLNKF
NTFAEPGPITNQTFLCSHGGIPPHKYHYIDDLVVILPQNVWEHLYNRFGGGPAVNHLYVC
SICQVEIEALAKRRRIEIDTFIKLNKAFQAEESPGVIYCISMQWFREWEAFVKGKDNEPP
GPIDNSRIAQVKGSGHVQLKQGADYGQISEETWTYLNSLYGGGPEIAIRQSVAQPLGPEN
LHGEQKIEAETRAV
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| BDBM50007790 |
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| n/a |
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| Name | BDBM50007790 |
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| Synonyms: | CHEMBL3233814 | med.21724, Compound 169 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27FN2O |
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| Mol. Mass. | 390.4931 |
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| SMILES | C[C@@H](N1CCC(CC1)C(=O)NCc1ccc(F)cc1)c1cccc2ccccc12 |r| |
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| Structure | 
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