| Reaction Details |
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 | Report a problem with these data |
| Target | Chromobox protein homolog 1 |
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| Ligand | BDBM50009555 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1336415 (CHEMBL3242419) |
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| Kd | >500000±n/a nM |
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| Citation |  Simhadri, C; Daze, KD; Douglas, SF; Quon, TT; Dev, A; Gignac, MC; Peng, F; Heller, M; Boulanger, MJ; Wulff, JE; Hof, F Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7). J Med Chem57:2874-83 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chromobox protein homolog 1 |
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| Name: | Chromobox protein homolog 1 |
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| Synonyms: | CBX | CBX1 | CBX1_HUMAN | HP1 beta | HP1Hsbeta | Heterochromatin protein 1 homolog beta | Heterochromatin protein p25 | M31 | Modifier 1 protein | p25beta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21405.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_103989 |
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| Residue: | 185 |
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| Sequence: | MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
PDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPE
RIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDK
KDDKN
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| BDBM50009555 |
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| n/a |
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| Name | BDBM50009555 |
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| Synonyms: | CHEMBL3234443 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H59N6O9 |
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| Mol. Mass. | 767.9307 |
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| SMILES | COC(=O)c1ccc(cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C1CCCC1)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)NC(CO)CO |r| |
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| Structure | 
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