Reaction Details |
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Target | Adenylate kinase 2, mitochondrial |
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Ligand | BDBM50010312 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1340550 (CHEMBL3254974) |
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Ki | 80000±n/a nM |
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Citation | Hampton, A; Picker, D Design of species- or isozyme-specific enzyme inhibitors. 3. Species and isozymic differences between mammalian and bacterial adenylate kinases in substituent tolerance in an enzyme-substrate complex. J Med Chem22:1529-32 (1980) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Adenylate kinase 2, mitochondrial |
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Name: | Adenylate kinase 2, mitochondrial |
Synonyms: | 2.7.4.3 | AK 2 | ATP-AMP transphosphorylase 2 | ATP:AMP phosphotransferase | Adenylate kinase 2 | Adenylate kinase 2, mitochondrial | Adenylate monophosphate kinase | Ak2 | KAD2_RAT |
Type: | n/a |
Mol. Mass.: | 26380.21 |
Organism: | Rattus norvegicus |
Description: | n/a |
Residue: | 239 |
Sequence: | MAPNALAPEPEHPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSEL
GKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKE
KLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNE
KALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSKATCKDLVMFV
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BDBM50010312 |
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n/a |
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Name | BDBM50010312 |
Synonyms: | CHEMBL3251360 |
Type | Small organic molecule |
Emp. Form. | C15H26N5O13P3S |
Mol. Mass. | 609.379 |
SMILES | CCCCCSc1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r| |
Structure |
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