Reaction Details |
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Target | GTP:AMP phosphotransferase AK3, mitochondrial |
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Ligand | BDBM50010313 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1340551 (CHEMBL3254975) |
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Ki | 220000±n/a nM |
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Citation | Hampton, A; Picker, D Design of species- or isozyme-specific enzyme inhibitors. 3. Species and isozymic differences between mammalian and bacterial adenylate kinases in substituent tolerance in an enzyme-substrate complex. J Med Chem22:1529-32 (1980) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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GTP:AMP phosphotransferase AK3, mitochondrial |
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Name: | GTP:AMP phosphotransferase AK3, mitochondrial |
Synonyms: | AK 3 | Adenylate kinase 3 | Adenylate kinase 3 alpha like 1 | Adenylate kinase 3 alpha-like 1 | Ak3 | Ak3l1 | Akl3l | GTP:AMP phosphotransferase mitochondrial | KAD3_RAT |
Type: | PROTEIN |
Mol. Mass.: | 25443.58 |
Organism: | Rattus norvegicus |
Description: | ChEMBL_1340551 |
Residue: | 227 |
Sequence: | MGASGRLLRAVIMGAPGSGKGTGSSRITKHFELKHLSSGDLLRQNMLQGTEIAVLAKSFI
DQGKLIPDDDMTRLALHELKNLTQCSWLLDGFPRTLPQAEALDRVYQIDTVINLNVPFEV
IKLRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQT
EPVLQYYQKKGVLETFSGTETNKIRPHVYSFLQMKVPETIQKASVTP
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BDBM50010313 |
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n/a |
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Name | BDBM50010313 |
Synonyms: | CHEMBL3251361 |
Type | Small organic molecule |
Emp. Form. | C12H20N5O14P3S |
Mol. Mass. | 583.299 |
SMILES | Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c(SCCO)nc12 |r| |
Structure |
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