Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGTP:AMP phosphotransferase AK3, mitochondrial
LigandBDBM50010313
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1340551 (CHEMBL3254975)
Ki 220000±n/a nM
Citation Hampton, APicker, D Design of species- or isozyme-specific enzyme inhibitors. 3. Species and isozymic differences between mammalian and bacterial adenylate kinases in substituent tolerance in an enzyme-substrate complex. J Med Chem22:1529-32 (1980) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
GTP:AMP phosphotransferase AK3, mitochondrial
Name:GTP:AMP phosphotransferase AK3, mitochondrial
Synonyms:AK 3 | Adenylate kinase 3 | Adenylate kinase 3 alpha like 1 | Adenylate kinase 3 alpha-like 1 | Ak3 | Ak3l1 | Akl3l | GTP:AMP phosphotransferase mitochondrial | KAD3_RAT
Type:PROTEIN
Mol. Mass.:25443.58
Organism:Rattus norvegicus
Description:ChEMBL_1340551
Residue:227
Sequence:
MGASGRLLRAVIMGAPGSGKGTGSSRITKHFELKHLSSGDLLRQNMLQGTEIAVLAKSFI
DQGKLIPDDDMTRLALHELKNLTQCSWLLDGFPRTLPQAEALDRVYQIDTVINLNVPFEV
IKLRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQT
EPVLQYYQKKGVLETFSGTETNKIRPHVYSFLQMKVPETIQKASVTP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50010313
n/a
NameBDBM50010313
Synonyms:CHEMBL3251361
TypeSmall organic molecule
Emp. Form.C12H20N5O14P3S
Mol. Mass.583.299
SMILESNc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c(SCCO)nc12 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: