| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM65830 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1352795 (CHEMBL3268195) |
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| IC50 | >32000±n/a nM |
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| Citation |  Urbano, M; Guerrero, M; Rosen, H; Roberts, E Antagonists of the kappa opioid receptor. Bioorg Med Chem Lett24:2021-32 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM65830 |
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| n/a |
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| Name | BDBM65830 |
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| Synonyms: | 4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[3-[(phenylmethyl)-propan-2-yl-amino]propyl]benzamide | 4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[3-[(phenylmethyl)-propan-2-ylamino]propyl]benzamide | KSC-5-249 | KUC103906N | N-[3-[benzyl(isopropyl)amino]propyl]-4-[(tosylamino)methyl]benzamide | N-[3-[benzyl(propan-2-yl)amino]propyl]-4-[[(4-methylphenyl)sulfonylamino]methyl]benzamide | cid_20968607 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H35N3O3S |
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| Mol. Mass. | 493.661 |
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| SMILES | CC(C)N(CCCNC(=O)c1ccc(CNS(=O)(=O)c2ccc(C)cc2)cc1)Cc1ccccc1 |
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| Structure | 
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