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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Coagulation factor X | ||
| Ligand | BDBM50017922 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1364435 (CHEMBL3294776) | ||
| Ki | 920±n/a nM | ||
| Citation |  Goswami, R; Mukherjee, S; Ghadiyaram, C; Wohlfahrt, G; Sistla, RK; Nagaraj, J; Satyam, LK; Subbarao, K; Palakurthy, RK; Gopinath, S; Krishnamurthy, NR; Ikonen, T; Moilanen, A; Subramanya, HS; Kallio, P; Ramachandra, M Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy. Bioorg Med Chem22:3187-203 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Coagulation factor X | |||
| Name: | Coagulation factor X | ||
| Synonyms: | Coagulation factor X | F10 | FA10_BOVIN | Factor Xa (fXa) | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 54498.45 | ||
| Organism: | Bos taurus | ||
| Description: | ChEMBL_1364435 | ||
| Residue: | 492 | ||
| Sequence: |
| ||
| BDBM50017922 | |||
| n/a | |||
| Name | BDBM50017922 | ||
| Synonyms: | CHEMBL3289025 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H31N5O4 | ||
| Mol. Mass. | 501.5768 | ||
| SMILES | NC(=N)c1ccc(Oc2cc(Oc3ccc(cc3)C(N)=N)cc(c2)C(=O)NCC2CCC(O)CC2)cc1 |(16.42,.39,;15.09,1.16,;15.09,2.7,;13.75,.39,;12.42,1.16,;11.08,.39,;11.08,-1.15,;9.75,-1.92,;9.75,-3.46,;8.42,-4.23,;8.42,-5.77,;7.08,-6.54,;5.75,-5.77,;4.42,-6.54,;3.08,-5.77,;3.08,-4.23,;4.42,-3.46,;5.75,-4.23,;1.75,-3.46,;.41,-4.23,;1.75,-1.92,;9.75,-6.54,;11.08,-5.77,;11.08,-4.23,;12.42,-6.54,;12.42,-8.08,;13.75,-5.77,;15.09,-6.54,;16.42,-5.77,;16.42,-4.23,;17.75,-3.46,;19.09,-4.23,;20.42,-3.46,;19.09,-5.77,;17.75,-6.54,;12.42,-1.92,;13.75,-1.15,)| | ||
| Structure | 
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