| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-7 |
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| Ligand | BDBM50430990 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1362841 (CHEMBL3295791) |
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| IC50 | 1440±n/a nM |
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| Citation |  Kawamura, S; Unno, Y; Asai, A; Arisawa, M; Shuto, S Development of a new class of proteasome inhibitors with an epoxyketone warhead: Rational hybridization of non-peptidic belactosin derivatives and peptide epoxyketones. Bioorg Med Chem22:3091-5 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-7 |
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| Name: | Proteasome subunit beta type-7 |
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| Synonyms: | Macropain chain Z | Multicatalytic endopeptidase complex chain Z | PSB7_HUMAN | PSMB7 | Proteasome subunit Z | Z |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29968.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_106197 |
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| Residue: | 277 |
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| Sequence: | MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGAD
TRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVV
TANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAV
FEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGT
RLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS
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| BDBM50430990 |
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| n/a |
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| Name | BDBM50430990 |
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| Synonyms: | BELACTOSIN A |
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| Type | Small organic molecule |
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| Emp. Form. | C17H27N3O6 |
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| Mol. Mass. | 369.4128 |
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| SMILES | CC[C@H](C)[C@H]1[C@@H](OC1=O)C(=O)N[C@H]1C[C@H]1C[C@H](NC(=O)[C@H](C)N)C(O)=O |r| |
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| Structure | 
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