| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2C8 |
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| Ligand | BDBM50020036 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1363752 (CHEMBL3293939) |
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| IC50 | >20000000±n/a nM |
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| Citation |  Cheng, L; Pettersen, D; Ohlsson, B; Schell, P; Karle, M; Evertsson, E; Pahlén, S; Jonforsen, M; Plowright, AT; Boström, J; Fex, T; Thelin, A; Hilgendorf, C; Xue, Y; Wahlund, G; Lindberg, W; Larsson, LO; Gustafsson, D Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein-Protein Interaction. ACS Med Chem Lett5:538-43 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2C8 |
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| Name: | Cytochrome P450 2C8 |
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| Synonyms: | CP2C8_HUMAN | CYP2C8 | CYPIIC8 | Cytochrome P450 2C8 (CYP2C8) | P450 IIC2 | P450 MP-12/MP-20 | P450 form 1 | S-mephenytoin 4-hydroxylase |
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| Type: | Protein |
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| Mol. Mass.: | 55839.23 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10632 |
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| Residue: | 490 |
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| Sequence: | MEPFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKV
YGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRW
KEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICS
VVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALT
RSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTE
TTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD
LVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFK
KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLP
PSYQICFIPV
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| BDBM50020036 |
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| n/a |
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| Name | BDBM50020036 |
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| Synonyms: | CHEMBL3287851 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H22N2O2 |
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| Mol. Mass. | 238.326 |
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| SMILES | CC(C)(C)C[C@H]1C[C@H](CCN1)c1cc(=O)[nH]o1 |r| |
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| Structure | 
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