| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM50020598 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1361904 (CHEMBL3293300) |
|---|
| Ki | 2398±n/a nM |
|---|
| Citation |  Pinna, G; Loriga, G; Lazzari, P; Ruiu, S; Falzoi, M; Frau, S; Pau, A; Murineddu, G; Asproni, B; Pinna, GA Tricyclic pyrazoles. Part 6. Benzofuro[3,2-c]pyrazole: a versatile architecture for CB2 selective ligands. Eur J Med Chem82:281-92 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52842.52 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P47746 |
|---|
| Residue: | 473 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM50020598 |
|---|
| n/a |
|---|
| Name | BDBM50020598 |
|---|
| Synonyms: | CHEMBL3290448 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H27Cl2N3O2 |
|---|
| Mol. Mass. | 496.428 |
|---|
| SMILES | C[C@@H]1C2CC(C[C@H]1NC(=O)c1nn(-c3ccc(Cl)cc3Cl)c3c1oc1cc(C)ccc31)C2(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
