Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMatrix protein 2
LigandBDBM50020755
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1364624 (CHEMBL3291757)
IC50 1240±n/a nM
Citation Rey-Carrizo, MBarniol-Xicota, MMa, CFrigolé-Vivas, MTorres, ENaesens, LLlabrés, SJuárez-Jiménez, JLuque, FJDeGrado, WFLamb, RAPinto, LHVázquez, S Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus. J Med Chem57:5738-47 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Matrix protein 2
Name:Matrix protein 2
Synonyms:M | M2_I72A8 | Proton channel protein M2
Type:PROTEIN
Mol. Mass.:11180.06
Organism:Influenza A virus (A/Udorn/307/1972(H3N2))
Description:ChEMBL_22
Residue:97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLK
RGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50020755
n/a
NameBDBM50020755
Synonyms:CHEMBL3286977
TypeSmall organic molecule
Emp. Form.C12H20ClN
Mol. Mass.213.747
SMILESCl.C1CC2C1C1CCC2C2CNCC12 |TLB:12:13:6.7:3.4,1:4:6.7:13.9,2:3:6.7:13.9,THB:10:9:6.7:3.4|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: