| Reaction Details |
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 | Report a problem with these data |
| Target | Matrix protein 2 |
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| Ligand | BDBM50033369 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1364624 (CHEMBL3291757) |
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| IC50 | 16000±n/a nM |
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| Citation |  Rey-Carrizo, M; Barniol-Xicota, M; Ma, C; Frigolé-Vivas, M; Torres, E; Naesens, L; Llabrés, S; Juárez-Jiménez, J; Luque, FJ; DeGrado, WF; Lamb, RA; Pinto, LH; Vázquez, S Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus. J Med Chem57:5738-47 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrix protein 2 |
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| Name: | Matrix protein 2 |
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| Synonyms: | M | M2_I72A8 | Proton channel protein M2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 11180.06 |
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| Organism: | Influenza A virus (A/Udorn/307/1972(H3N2)) |
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| Description: | ChEMBL_22 |
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| Residue: | 97 |
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| Sequence: | MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLK
RGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
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| BDBM50033369 |
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| n/a |
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| Name | BDBM50033369 |
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| Synonyms: | AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL |
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| Type | Small organic molecule |
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| Emp. Form. | C10H17N |
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| Mol. Mass. | 151.2487 |
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| SMILES | NC12CC3CC(CC(C3)C1)C2 |THB:6:5:2:8.7.9,6:7:4.5.10:2,9:7:4:10.1.2,9:1:4:8.6.7,0:1:4:8.6.7| |
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| Structure | 
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