| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 5 |
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| Ligand | BDBM50022109 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1367553 |
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| IC50 | 25±n/a nM |
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| Citation |  Johnson, JA; Xu, N; Jeon, Y; Finlay, HJ; Kover, A; Conder, ML; Sun, H; Li, D; Levesque, P; Hsueh, MM; Harper, TW; Wexler, RR; Lloyd, J Design, synthesis and evaluation of phenethylaminoheterocycles as K(v)1.5 inhibitors. Bioorg Med Chem Lett24:3018-22 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 5 |
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| Name: | Potassium voltage-gated channel subfamily A member 5 |
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| Synonyms: | HK2 | HPCN1 | KCNA5 | KCNA5_HUMAN | Potassium voltage-gated channel subfamily A member 5 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.5 |
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| Type: | Enzyme |
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| Mol. Mass.: | 67222.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22460 |
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| Residue: | 613 |
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| Sequence: | MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
YALCLDTSRETDL
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| BDBM50022109 |
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| n/a |
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| Name | BDBM50022109 |
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| Synonyms: | CHEMBL3298224 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N2S |
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| Mol. Mass. | 310.456 |
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| SMILES | CCc1cccc2snc(NCC(C)(C)c3ccccc3)c12 |
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| Structure | 
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