Compile Data Set for Download or QSAR

Found 258 hits with Last Name = 'conder' and Initial = 'ml'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106179 (CHEMBL125327 | Enantiomer-4-(3-Butyl-[1,2,4]oxadia...) Show SMILES CCCCc1noc(n1)-c1ccc(cc1)C(=O)NC[C@H]1CCCC1(C)C Show InChI InChI=1S/C21H29N3O2/c1-4-5-8-18-23-20(26-24-18)16-11-9-15(10-12-16)19(25)22-14-17-7-6-13-21(17,2)3/h9-12,17H,4-8,13-14H2,1-3H3,(H,22,25)/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106169 (CHEMBL338973 | Enantiomer-4-(3-Butyl-[1,2,4]oxadia...) Show SMILES CCCCc1noc(n1)-c1ccc(cc1)C(=O)NC[C@@H]1CCCC1(C)C Show InChI InChI=1S/C21H29N3O2/c1-4-5-8-18-23-20(26-24-18)16-11-9-15(10-12-16)19(25)22-14-17-7-6-13-21(17,2)3/h9-12,17H,4-8,13-14H2,1-3H3,(H,22,25)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106167 (CHEMBL125000 | Enantiomer-4-(3-Cyclopropylmethyl-[...) Show SMILES CC1(C)CCCC1CNC(=O)c1ccc(cc1)-c1nc(CC2CC2)no1 Show InChI InChI=1S/C21H27N3O2/c1-21(2)11-3-4-17(21)13-22-19(25)15-7-9-16(10-8-15)20-23-18(24-26-20)12-14-5-6-14/h7-10,14,17H,3-6,11-13H2,1-2H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106167 (CHEMBL125000 | Enantiomer-4-(3-Cyclopropylmethyl-[...) Show SMILES CC1(C)CCCC1CNC(=O)c1ccc(cc1)-c1nc(CC2CC2)no1 Show InChI InChI=1S/C21H27N3O2/c1-21(2)11-3-4-17(21)13-22-19(25)15-7-9-16(10-8-15)20-23-18(24-26-20)12-14-5-6-14/h7-10,14,17H,3-6,11-13H2,1-2H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptor				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50022107 (CHEMBL3298226) Show SMILES COc1cccc2ccnc(NCC(C)(C)c3ccccc3)c12 Show InChI InChI=1S/C20H22N2O/c1-20(2,16-9-5-4-6-10-16)14-22-19-18-15(12-13-21-19)8-7-11-17(18)23-3/h4-13H,14H2,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of current				Bioorg Med Chem Lett 24: 3018-22 (2014) Article DOI: 10.1016/j.bmcl.2014.05.035 BindingDB Entry DOI: 10.7270/Q2HH6MNP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106178 (4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(3,3-dimethyl-...) Show SMILES CCCCc1noc(n1)-c1ccc(cc1)C(=O)NCCC(C)(C)C Show InChI InChI=1S/C19H27N3O2/c1-5-6-7-16-21-18(24-22-16)15-10-8-14(9-11-15)17(23)20-13-12-19(2,3)4/h8-11H,5-7,12-13H2,1-4H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50022108 (CHEMBL3298228) Show SMILES COc1cccc2nc(O)nc(NCC(C)(C)c3ccccc3)c12 Show InChI InChI=1S/C19H21N3O2/c1-19(2,13-8-5-4-6-9-13)12-20-17-16-14(21-18(23)22-17)10-7-11-15(16)24-3/h4-11H,12H2,1-3H3,(H2,20,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of current				Bioorg Med Chem Lett 24: 3018-22 (2014) Article DOI: 10.1016/j.bmcl.2014.05.035 BindingDB Entry DOI: 10.7270/Q2HH6MNP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120918 (CHEMBL3356073) Show SMILES COc1cccc2snc(NCC(C)(C)c3ccccc3)c12 Show InChI InChI=1S/C18H20N2OS/c1-18(2,13-8-5-4-6-9-13)12-19-17-16-14(21-3)10-7-11-15(16)22-20-17/h4-11H,12H2,1-3H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50022109 (CHEMBL3298224) Show SMILES CCc1cccc2snc(NCC(C)(C)c3ccccc3)c12 Show InChI InChI=1S/C19H22N2S/c1-4-14-9-8-12-16-17(14)18(21-22-16)20-13-19(2,3)15-10-6-5-7-11-15/h5-12H,4,13H2,1-3H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of current				Bioorg Med Chem Lett 24: 3018-22 (2014) Article DOI: 10.1016/j.bmcl.2014.05.035 BindingDB Entry DOI: 10.7270/Q2HH6MNP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106168 (CHEMBL124448 | Enantiomer-N-(2,2-Dimethyl-cyclopen...) Show SMILES CCCc1noc(n1)-c1ccc(cc1)C(=O)NCC1CCCC1(C)C Show InChI InChI=1S/C20H27N3O2/c1-4-6-17-22-19(25-23-17)15-10-8-14(9-11-15)18(24)21-13-16-7-5-12-20(16,2)3/h8-11,16H,4-7,12-13H2,1-3H3,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106168 (CHEMBL124448 | Enantiomer-N-(2,2-Dimethyl-cyclopen...) Show SMILES CCCc1noc(n1)-c1ccc(cc1)C(=O)NCC1CCCC1(C)C Show InChI InChI=1S/C20H27N3O2/c1-4-6-17-22-19(25-23-17)15-10-8-14(9-11-15)18(24)21-13-16-7-5-12-20(16,2)3/h8-11,16H,4-7,12-13H2,1-3H3,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptor				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120913 (CHEMBL3622361) Show SMILES COc1cccc2c1C(NC[C@@]1(CC[C@@H](CC1)NC(=O)OCC(F)(F)F)c1ccccc1)=NS2(=O)=O |r,wU:14.18,11.11,c:34,(-2.09,3.71,;-1.02,3.09,;-1.03,1.55,;-2.38,.77,;-2.38,-.77,;-1.03,-1.55,;.3,-.77,;.3,.77,;1.76,1.24,;2.24,2.7,;3.75,3.01,;4.23,4.48,;4.74,5.91,;3.71,7.06,;2.2,6.74,;1.72,5.28,;2.75,4.13,;1.18,7.89,;1.66,9.35,;2.87,9.6,;.63,10.5,;1.12,11.97,;.09,13.12,;.48,14.29,;-.73,14.04,;-1.11,12.87,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,)| Show InChI InChI=1S/C24H26F3N3O5S/c1-34-18-8-5-9-19-20(18)21(30-36(19,32)33)28-14-23(16-6-3-2-4-7-16)12-10-17(11-13-23)29-22(31)35-15-24(25,26)27/h2-9,17H,10-15H2,1H3,(H,28,30)(H,29,31)/t17-,23-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120899 (CHEMBL3622355) Show SMILES COc1cccc2c1C(NC[C@@]1(CC[C@@H](CC1)OC(=O)Nc1ccc(cc1)N(C)C)c1ccccc1)=NS2(=O)=O |r,wU:14.18,11.11,c:39,(-2.09,3.71,;-1.02,3.09,;-1.03,1.55,;-2.38,.77,;-2.38,-.77,;-1.03,-1.55,;.3,-.77,;.3,.77,;1.76,1.24,;2.24,2.7,;3.75,3.01,;4.23,4.48,;4.74,5.91,;3.71,7.06,;2.2,6.74,;1.72,5.28,;2.75,4.13,;1.18,7.89,;1.66,9.35,;2.87,9.6,;.63,10.5,;1.12,11.97,;.09,13.12,;.58,14.58,;2.09,14.89,;3.11,13.74,;2.63,12.28,;2.58,16.35,;3.78,16.6,;1.76,17.27,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,)| Show InChI InChI=1S/C30H34N4O5S/c1-34(2)23-14-12-22(13-15-23)32-29(35)39-24-16-18-30(19-17-24,21-8-5-4-6-9-21)20-31-28-27-25(38-3)10-7-11-26(27)40(36,37)33-28/h4-15,24H,16-20H2,1-3H3,(H,31,33)(H,32,35)/t24-,30-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50061218 ((E)-3-(2,4-Dichloro-phenyl)-N-((R)-1-methyl-2-oxo-...) Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)\C=C\c2ccc(Cl)cc2Cl)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C25H19Cl2N3O2/c1-30-21-10-6-5-9-19(21)23(17-7-3-2-4-8-17)29-24(25(30)32)28-22(31)14-12-16-11-13-18(26)15-20(16)27/h2-15,24H,1H3,(H,28,31)/b14-12+/t24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120908 (CHEMBL3623054) Show SMILES COc1cccc2c1C(NC[C@@]1(CC[C@@H](CC1)n1cnnn1)c1ccccc1)=NS2(=O)=O |r,wU:14.18,11.11,c:31,(-2.09,3.71,;-1.02,3.09,;-1.03,1.55,;-2.38,.77,;-2.38,-.77,;-1.03,-1.55,;.3,-.77,;.3,.77,;1.76,1.24,;2.24,2.7,;3.75,3.01,;4.23,4.48,;4.74,5.91,;3.71,7.06,;2.2,6.74,;1.72,5.28,;2.75,4.13,;1.17,7.89,;1.52,9.38,;.19,10.15,;-.96,9.13,;-.34,7.72,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,)| Show InChI InChI=1S/C22H24N6O3S/c1-31-18-8-5-9-19-20(18)21(25-32(19,29)30)23-14-22(16-6-3-2-4-7-16)12-10-17(11-13-22)28-15-24-26-27-28/h2-9,15,17H,10-14H2,1H3,(H,23,25)/t17-,22-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50099581 (CHEMBL288131 | N-((2R,3R)-3-(4-ethylphenylsulfonam...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)Cc2ccc(NC(=O)c3cccc(OC)c3)cc12 |r| Show InChI InChI=1S/C25H26N2O5S/c1-3-16-7-11-21(12-8-16)33(30,31)27-24-22-15-19(10-9-17(22)14-23(24)28)26-25(29)18-5-4-6-20(13-18)32-2/h4-13,15,23-24,27-28H,3,14H2,1-2H3,(H,26,29)/t23-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120904 (CHEMBL3622346) Show SMILES COc1cccc2c1C(NC[C@@]1(CC[C@H](O)CC1)c1ccccc1)=NS2(=O)=O |r,wU:14.15,11.11,c:26,(-2.09,3.71,;-1.02,3.09,;-1.03,1.55,;-2.38,.77,;-2.38,-.77,;-1.03,-1.55,;.3,-.77,;.3,.77,;1.76,1.24,;2.24,2.7,;3.75,3.01,;4.23,4.48,;4.74,5.91,;3.71,7.06,;2.2,6.74,;1.38,7.66,;1.72,5.28,;2.75,4.13,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,)| Show InChI InChI=1S/C21H24N2O4S/c1-27-17-8-5-9-18-19(17)20(23-28(18,25)26)22-14-21(12-10-16(24)11-13-21)15-6-3-2-4-7-15/h2-9,16,24H,10-14H2,1H3,(H,22,23)/t16-,21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120917 (CHEMBL3356074) Show SMILES COc1cccc2C(=O)N=C(NCC(C)(C)c3ccccc3)c12 |t:9| Show InChI InChI=1S/C19H20N2O2/c1-19(2,13-8-5-4-6-9-13)12-20-17-16-14(18(22)21-17)10-7-11-15(16)23-3/h4-11H,12H2,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50430217 (CHEMBL2331989) Show SMILES CC1=Nc2ccnn2[C@@H](C1c1ncnn1C1CCCC1)c1ccc(Cl)c(Cl)c1 |r,t:1| Show InChI InChI=1S/C20H20Cl2N6/c1-12-18(20-23-11-25-27(20)14-4-2-3-5-14)19(28-17(26-12)8-9-24-28)13-6-7-15(21)16(22)10-13/h6-11,14,18-19H,2-5H2,1H3/t18?,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp as...				Bioorg Med Chem Lett 23: 1743-7 (2013) Article DOI: 10.1016/j.bmcl.2013.01.064 BindingDB Entry DOI: 10.7270/Q2QN685H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106176 (CHEMBL340681 | Enantiomer-N-(2,2-Dimethyl-cyclopen...) Show SMILES CC1(C)CCCC1CNC(=O)c1ccc(cc1)-c1noc(CCC(F)(F)F)n1 Show InChI InChI=1S/C20H24F3N3O2/c1-19(2)10-3-4-15(19)12-24-18(27)14-7-5-13(6-8-14)17-25-16(28-26-17)9-11-20(21,22)23/h5-8,15H,3-4,9-12H2,1-2H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106176 (CHEMBL340681 | Enantiomer-N-(2,2-Dimethyl-cyclopen...) Show SMILES CC1(C)CCCC1CNC(=O)c1ccc(cc1)-c1noc(CCC(F)(F)F)n1 Show InChI InChI=1S/C20H24F3N3O2/c1-19(2)10-3-4-15(19)12-24-18(27)14-7-5-13(6-8-14)17-25-16(28-26-17)9-11-20(21,22)23/h5-8,15H,3-4,9-12H2,1-2H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Bindind affinity values obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from a preparation of whole rat brain				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50534219 (CHEMBL4521294) Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1ccncc1)c1ccccn1 Show InChI InChI=1S/C25H19N5/c1-2-7-18(8-3-1)21-10-6-11-22-23(21)25(28-17-20-9-4-5-14-27-20)30-24(29-22)19-12-15-26-16-13-19/h1-16H,17H2,(H,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 transfected in mouse LTK cells				ACS Med Chem Lett 7: 831-4 (2016) Article DOI: 10.1021/acsmedchemlett.6b00117 BindingDB Entry DOI: 10.7270/Q2MK6HDX
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50022110 (CHEMBL3298140) Show SMILES COc1cccc2onc(NCC(C)(C)c3ccccc3)c12 Show InChI InChI=1S/C18H20N2O2/c1-18(2,13-8-5-4-6-9-13)12-19-17-16-14(21-3)10-7-11-15(16)22-20-17/h4-11H,12H2,1-3H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of current				Bioorg Med Chem Lett 24: 3018-22 (2014) Article DOI: 10.1016/j.bmcl.2014.05.035 BindingDB Entry DOI: 10.7270/Q2HH6MNP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50022110 (CHEMBL3298140) Show SMILES COc1cccc2onc(NCC(C)(C)c3ccccc3)c12 Show InChI InChI=1S/C18H20N2O2/c1-18(2,13-8-5-4-6-9-13)12-19-17-16-14(21-3)10-7-11-15(16)22-20-17/h4-11H,12H2,1-3H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50376745 (CHEMBL260684) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1CCCc2ccc(cc12)N(Cc1cccc(C)n1)C(=O)CCc1ccccc1 Show InChI InChI=1S/C34H37N3O3S/c1-3-26-15-20-31(21-16-26)41(39,40)36-33-14-8-12-28-18-19-30(23-32(28)33)37(24-29-13-7-9-25(2)35-29)34(38)22-17-27-10-5-4-6-11-27/h4-7,9-11,13,15-16,18-21,23,33,36H,3,8,12,14,17,22,24H2,1-2H3/t33-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells assessed as blockade of ultra rapidly activating potassium current by volatge clamp t...				Bioorg Med Chem Lett 18: 2714-8 (2008) Article DOI: 10.1016/j.bmcl.2008.03.026 BindingDB Entry DOI: 10.7270/Q2QC04DZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120907 (CHEMBL3623053) Show SMILES COc1cccc2c1C(NC[C@@]1(CC[C@@H](CC1)Nc1ncccn1)c1ccccc1)=NS2(=O)=O |r,wU:14.18,11.11,c:33,(-2.09,3.71,;-1.02,3.09,;-1.03,1.55,;-2.38,.77,;-2.38,-.77,;-1.03,-1.55,;.3,-.77,;.3,.77,;1.76,1.24,;2.24,2.7,;3.75,3.01,;4.23,4.48,;4.74,5.91,;3.71,7.06,;2.2,6.74,;1.72,5.28,;2.75,4.13,;1.18,7.89,;1.66,9.35,;.64,10.51,;1.12,11.97,;2.63,12.28,;3.65,11.13,;3.17,9.66,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,)| Show InChI InChI=1S/C25H27N5O3S/c1-33-20-9-5-10-21-22(20)23(30-34(21,31)32)28-17-25(18-7-3-2-4-8-18)13-11-19(12-14-25)29-24-26-15-6-16-27-24/h2-10,15-16,19H,11-14,17H2,1H3,(H,28,30)(H,26,27,29)/t19-,25-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50430216 (CHEMBL2331990) Show SMILES CC1=Nc2ccnn2[C@@H](C1c1ncnn1C1CCC1)c1ccc(Cl)c(Cl)c1 |r,t:1| Show InChI InChI=1S/C19H18Cl2N6/c1-11-17(19-22-10-24-26(19)13-3-2-4-13)18(27-16(25-11)7-8-23-27)12-5-6-14(20)15(21)9-12/h5-10,13,17-18H,2-4H2,1H3/t17?,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp as...				Bioorg Med Chem Lett 23: 1743-7 (2013) Article DOI: 10.1016/j.bmcl.2013.01.064 BindingDB Entry DOI: 10.7270/Q2QN685H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50534218 (CHEMBL4532101) Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncs1)c1ccccn1 Show InChI InChI=1S/C23H17N5S/c1-2-7-16(8-3-1)18-10-6-11-19-21(18)23(26-13-17-9-4-5-12-25-17)28-22(27-19)20-14-24-15-29-20/h1-12,14-15H,13H2,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 transfected in mouse LTK cells				ACS Med Chem Lett 7: 831-4 (2016) Article DOI: 10.1021/acsmedchemlett.6b00117 BindingDB Entry DOI: 10.7270/Q2MK6HDX
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50534225 (CHEMBL4450487) Show SMILES N#Cc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1 Show InChI InChI=1S/C21H15N5/c22-13-19-25-18-11-6-10-17(15-7-2-1-3-8-15)20(18)21(26-19)24-14-16-9-4-5-12-23-16/h1-12H,14H2,(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 transfected in mouse LTK cells				ACS Med Chem Lett 7: 831-4 (2016) Article DOI: 10.1021/acsmedchemlett.6b00117 BindingDB Entry DOI: 10.7270/Q2MK6HDX
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50099581 (CHEMBL288131 | N-((2R,3R)-3-(4-ethylphenylsulfonam...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)Cc2ccc(NC(=O)c3cccc(OC)c3)cc12 |r| Show InChI InChI=1S/C25H26N2O5S/c1-3-16-7-11-21(12-8-16)33(30,31)27-24-22-15-19(10-9-17(22)14-23(24)28)26-25(29)18-5-4-6-20(13-18)32-2/h4-13,15,23-24,27-28H,3,14H2,1-2H3,(H,26,29)/t23-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells assessed as blockade of ultra rapidly activating potassium current by volatge clamp t...				Bioorg Med Chem Lett 18: 2714-8 (2008) Article DOI: 10.1016/j.bmcl.2008.03.026 BindingDB Entry DOI: 10.7270/Q2QC04DZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306906 (((R)-7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropy...) Show SMILES CC1=Nc2ccnn2[C@@H](C1C(=O)N1CCC[C@H]1c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1 |r,t:1| Show InChI InChI=1S/C24H21Cl2FN4O/c1-14-22(24(32)30-12-2-3-20(30)15-4-7-17(27)8-5-15)23(31-21(29-14)10-11-28-31)16-6-9-18(25)19(26)13-16/h4-11,13,20,22-23H,2-3,12H2,1H3/t20-,22?,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120903 (CHEMBL3622360) Show SMILES COc1cccc2c1C(NC[C@@]1(CC[C@@H](CC1)NC(=O)OC(C)C)c1ccccc1)=NS2(=O)=O |r,wU:14.18,11.11,c:32,(-2.09,3.71,;-1.02,3.09,;-1.03,1.55,;-2.38,.77,;-2.38,-.77,;-1.03,-1.55,;.3,-.77,;.3,.77,;1.76,1.24,;2.24,2.7,;3.75,3.01,;4.23,4.48,;4.74,5.91,;3.71,7.06,;2.2,6.74,;1.72,5.28,;2.75,4.13,;1.18,7.89,;1.66,9.35,;2.87,9.6,;.63,10.5,;1.12,11.97,;.3,12.89,;2.32,12.22,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,)| Show InChI InChI=1S/C25H31N3O5S/c1-17(2)33-24(29)27-19-12-14-25(15-13-19,18-8-5-4-6-9-18)16-26-23-22-20(32-3)10-7-11-21(22)34(30,31)28-23/h4-11,17,19H,12-16H2,1-3H3,(H,26,28)(H,27,29)/t19-,25-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120916 (CHEMBL3623052) Show SMILES CCN(CC)S(=O)(=O)N[C@H]1CC[C@@](CNC2=NS(=O)(=O)c3cccc(OC)c23)(CC1)c1ccccc1 |r,wU:9.8,12.12,t:15,(.3,12.89,;1.12,11.97,;.63,10.5,;-.87,10.19,;-1.69,11.11,;1.66,9.35,;2.87,9.6,;2.48,8.44,;1.18,7.89,;2.2,6.74,;3.71,7.06,;4.74,5.91,;4.23,4.48,;3.75,3.01,;2.24,2.7,;1.76,1.24,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,;.3,-.77,;-1.03,-1.55,;-2.38,-.77,;-2.38,.77,;-1.03,1.55,;-1.02,3.09,;-2.09,3.71,;.3,.77,;2.75,4.13,;1.72,5.28,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,)| Show InChI InChI=1S/C25H34N4O5S2/c1-4-29(5-2)36(32,33)27-20-14-16-25(17-15-20,19-10-7-6-8-11-19)18-26-24-23-21(34-3)12-9-13-22(23)35(30,31)28-24/h6-13,20,27H,4-5,14-18H2,1-3H3,(H,26,28)/t20-,25-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120901 (CHEMBL3622358) Show SMILES CCOC(=O)N[C@H]1CC[C@@](CNC2=NS(=O)(=O)c3cccc(OC)c23)(CC1)c1ccccc1 |r,wU:6.5,9.9,t:12,(.3,12.89,;1.12,11.97,;.63,10.5,;1.66,9.35,;2.87,9.6,;1.18,7.89,;2.2,6.74,;3.71,7.06,;4.74,5.91,;4.23,4.48,;3.75,3.01,;2.24,2.7,;1.76,1.24,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,;.3,-.77,;-1.03,-1.55,;-2.38,-.77,;-2.38,.77,;-1.03,1.55,;-1.02,3.09,;-2.09,3.71,;.3,.77,;2.75,4.13,;1.72,5.28,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,)| Show InChI InChI=1S/C24H29N3O5S/c1-3-32-23(28)26-18-12-14-24(15-13-18,17-8-5-4-6-9-17)16-25-22-21-19(31-2)10-7-11-20(21)33(29,30)27-22/h4-11,18H,3,12-16H2,1-2H3,(H,25,27)(H,26,28)/t18-,24-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211550 ((3S,4R)-4-(N-butyl-4-ethylphenylsulfonamido)-3-hyd...) Show SMILES CCCCN([C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)NCCc1ccccc1)S(=O)(=O)c1ccc(CC)cc1 Show InChI InChI=1S/C32H40N2O5S/c1-5-7-21-34(40(37,38)26-16-13-23(6-2)14-17-26)29-27-22-25(15-18-28(27)39-32(3,4)30(29)35)31(36)33-20-19-24-11-9-8-10-12-24/h8-18,22,29-30,35H,5-7,19-21H2,1-4H3,(H,33,36)/t29-,30+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50430219 (CHEMBL2331987) Show SMILES CC1=Nc2ccnn2[C@@H](C1c1ncnn1C1CCCCC1)c1ccc(Cl)c(Cl)c1 |r,t:1| Show InChI InChI=1S/C21H22Cl2N6/c1-13-19(21-24-12-26-28(21)15-5-3-2-4-6-15)20(29-18(27-13)9-10-25-29)14-7-8-16(22)17(23)11-14/h7-12,15,19-20H,2-6H2,1H3/t19?,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp as...				Bioorg Med Chem Lett 23: 1743-7 (2013) Article DOI: 10.1016/j.bmcl.2013.01.064 BindingDB Entry DOI: 10.7270/Q2QN685H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120914 (CHEMBL3622362) Show SMILES CCS(=O)(=O)N[C@H]1CC[C@@](CNC2=NS(=O)(=O)c3cccc(OC)c23)(CC1)c1ccccc1 |r,wU:6.5,9.9,t:12,(1.02,11.67,;.63,10.5,;1.66,9.35,;2.87,9.6,;2.48,8.44,;1.18,7.89,;2.2,6.74,;3.71,7.06,;4.74,5.91,;4.23,4.48,;3.75,3.01,;2.24,2.7,;1.76,1.24,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,;.3,-.77,;-1.03,-1.55,;-2.38,-.77,;-2.38,.77,;-1.03,1.55,;-1.02,3.09,;-2.09,3.71,;.3,.77,;2.75,4.13,;1.72,5.28,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,)| Show InChI InChI=1S/C23H29N3O5S2/c1-3-32(27,28)25-18-12-14-23(15-13-18,17-8-5-4-6-9-17)16-24-22-21-19(31-2)10-7-11-20(21)33(29,30)26-22/h4-11,18,25H,3,12-16H2,1-2H3,(H,24,26)/t18-,23-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50239231 (CHEMBL4099807) Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cccnc1)c1ccccn1 Show InChI InChI=1S/C25H19N5/c1-2-8-18(9-3-1)21-12-6-13-22-23(21)25(28-17-20-11-4-5-15-27-20)30-24(29-22)19-10-7-14-26-16-19/h1-16H,17H2,(H,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 transfected in mouse LTK cells				ACS Med Chem Lett 7: 831-4 (2016) Article DOI: 10.1021/acsmedchemlett.6b00117 BindingDB Entry DOI: 10.7270/Q2MK6HDX
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211535 (CHEMBL387993 | N-((3S,4R)-6-((S)-2-((2,6-dimethylp...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)N1CCC[C@H]1CNc1c(C)cccc1C Show InChI InChI=1S/C33H41N3O5S/c1-6-23-12-15-26(16-13-23)42(39,40)35-30-27-19-24(14-17-28(27)41-33(4,5)31(30)37)32(38)36-18-8-11-25(36)20-34-29-21(2)9-7-10-22(29)3/h7,9-10,12-17,19,25,30-31,34-35,37H,6,8,11,18,20H2,1-5H3/t25-,30+,31-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells assessed as blockade of ultra rapidly activating potassium current by volatge clamp t...				Bioorg Med Chem Lett 18: 2714-8 (2008) Article DOI: 10.1016/j.bmcl.2008.03.026 BindingDB Entry DOI: 10.7270/Q2QC04DZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50120909 (CHEMBL3622348) Show SMILES CCNC(=O)O[C@H]1CC[C@@](CNC2=NS(=O)(=O)c3cccc(OC)c23)(CC1)c1ccccc1 |r,wU:6.5,9.9,t:12,(.3,12.89,;1.12,11.97,;.63,10.5,;1.66,9.35,;2.87,9.6,;1.18,7.89,;2.2,6.74,;3.71,7.06,;4.74,5.91,;4.23,4.48,;3.75,3.01,;2.24,2.7,;1.76,1.24,;2.66,.02,;1.76,-1.24,;.93,-2.14,;2.97,-1.47,;.3,-.77,;-1.03,-1.55,;-2.38,-.77,;-2.38,.77,;-1.03,1.55,;-1.02,3.09,;-2.09,3.71,;.3,.77,;2.75,4.13,;1.72,5.28,;5.74,4.79,;6.76,3.65,;8.27,3.96,;8.75,5.43,;7.72,6.57,;6.22,6.26,)| Show InChI InChI=1S/C24H29N3O5S/c1-3-25-23(28)32-18-12-14-24(15-13-18,17-8-5-4-6-9-17)16-26-22-21-19(31-2)10-7-11-20(21)33(29,30)27-22/h4-11,18H,3,12-16H2,1-2H3,(H,25,28)(H,26,27)/t18-,24-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human KV1.5 expressed in mouse L929 cells assessed as decrease in ultrarapid potassium current amplitude				Bioorg Med Chem Lett 25: 4983-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.066 BindingDB Entry DOI: 10.7270/Q2HH6MWT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM357015 (US10214511, Example 19 | US10676460, Example 19) Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1 Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 transfected in mouse LTK cells				ACS Med Chem Lett 7: 831-4 (2016) Article DOI: 10.1021/acsmedchemlett.6b00117 BindingDB Entry DOI: 10.7270/Q2MK6HDX
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50385935 (CHEMBL2042152) Show SMILES COCC1=Nc2ccnn2[C@@H](C1C(=O)N1CCC[C@H]1c1cc(C)no1)c1ccc(Cl)c(Cl)c1 |r,t:3| Show InChI InChI=1S/C23H23Cl2N5O3/c1-13-10-19(33-28-13)18-4-3-9-29(18)23(31)21-17(12-32-2)27-20-7-8-26-30(20)22(21)14-5-6-15(24)16(25)11-14/h5-8,10-11,18,21-22H,3-4,9,12H2,1-2H3/t18-,21?,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human KV1.5 ion channel expressed in mouse L929 cells by whole cell patch clamp assay				J Med Chem 55: 3036-48 (2012) Article DOI: 10.1021/jm201386u BindingDB Entry DOI: 10.7270/Q2KK9CTG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306891 ((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCCC1c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C24H21Cl2FN4O/c1-14-22(24(32)30-12-2-3-20(30)15-4-7-17(27)8-5-15)23(31-21(29-14)10-11-28-31)16-6-9-18(25)19(26)13-16/h4-11,13,20,22-23H,2-3,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306891 ((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCCC1c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C24H21Cl2FN4O/c1-14-22(24(32)30-12-2-3-20(30)15-4-7-17(27)8-5-15)23(31-21(29-14)10-11-28-31)16-6-9-18(25)19(26)13-16/h4-11,13,20,22-23H,2-3,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254809 ((R)-(7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropy...) Show SMILES CC1=Nc2ccnn2[C@@H](C1C(=O)N1CCN(CC1)c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1 |r,t:1| Show InChI InChI=1S/C24H22Cl2FN5O/c1-15-22(24(33)31-12-10-30(11-13-31)18-5-3-17(27)4-6-18)23(32-21(29-15)8-9-28-32)16-2-7-19(25)20(26)14-16/h2-9,14,22-23H,10-13H2,1H3/t22?,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique				Bioorg Med Chem Lett 18: 6381-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.099 BindingDB Entry DOI: 10.7270/Q2WW7HH7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254617 (7-(3,4-dichlorophenyl)-5-methyl-N,N-dipropyl-4,7-d...) Show SMILES CCCN(CCC)C(=O)C1C(c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |c:26| Show InChI InChI=1S/C20H24Cl2N4O/c1-4-10-25(11-5-2)20(27)18-13(3)24-17-8-9-23-26(17)19(18)14-6-7-15(21)16(22)12-14/h6-9,12,18-19H,4-5,10-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique				Bioorg Med Chem Lett 18: 6381-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.099 BindingDB Entry DOI: 10.7270/Q2WW7HH7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50385942 (CHEMBL2042162) Show SMILES Cc1cc(on1)[C@@H]1CCCN1C(=O)C1[C@@H](c2cc3ccccc3n2C)n2nc(cc2N=C1C)C(F)(F)F |r,c:35| Show InChI InChI=1S/C26H25F3N6O2/c1-14-11-20(37-32-14)18-9-6-10-34(18)25(36)23-15(2)30-22-13-21(26(27,28)29)31-35(22)24(23)19-12-16-7-4-5-8-17(16)33(19)3/h4-5,7-8,11-13,18,23-24H,6,9-10H2,1-3H3/t18-,23?,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human KV1.5 ion channel expressed in mouse L929 cells by whole cell patch clamp assay				J Med Chem 55: 3036-48 (2012) Article DOI: 10.1021/jm201386u BindingDB Entry DOI: 10.7270/Q2KK9CTG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50022111 (CHEMBL3298227) Show SMILES COc1cccc2nc(Cl)nc(NCC(C)(C)c3ccccc3)c12 Show InChI InChI=1S/C19H20ClN3O/c1-19(2,13-8-5-4-6-9-13)12-21-17-16-14(22-18(20)23-17)10-7-11-15(16)24-3/h4-11H,12H2,1-3H3,(H,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of current				Bioorg Med Chem Lett 24: 3018-22 (2014) Article DOI: 10.1016/j.bmcl.2014.05.035 BindingDB Entry DOI: 10.7270/Q2HH6MNP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50430227 (CHEMBL2332455) Show SMILES CC1=Nc2ccnn2[C@@H](C1c1ncnn1-c1ccccc1F)c1ccc(Cl)c(Cl)c1 |r,t:1| Show InChI InChI=1S/C21H15Cl2FN6/c1-12-19(21-25-11-27-29(21)17-5-3-2-4-16(17)24)20(30-18(28-12)8-9-26-30)13-6-7-14(22)15(23)10-13/h2-11,19-20H,1H3/t19?,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp as...				Bioorg Med Chem Lett 23: 1743-7 (2013) Article DOI: 10.1016/j.bmcl.2013.01.064 BindingDB Entry DOI: 10.7270/Q2QN685H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211518 ((3S,4R)-N-ethyl-4-(4-ethylphenylsulfonamido)-3-hyd...) Show SMILES CCN(CCNc1ccccc1)C(=O)c1ccc2OC(C)(C)[C@@H](O)[C@H](NS(=O)(=O)c3ccc(CC)cc3)c2c1 Show InChI InChI=1S/C30H37N3O5S/c1-5-21-12-15-24(16-13-21)39(36,37)32-27-25-20-22(14-17-26(25)38-30(3,4)28(27)34)29(35)33(6-2)19-18-31-23-10-8-7-9-11-23/h7-17,20,27-28,31-32,34H,5-6,18-19H2,1-4H3/t27-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair

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