| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 5 |
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| Ligand | BDBM50430217 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_943345 (CHEMBL2340853) |
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| IC50 | 37±n/a nM |
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| Citation |  Finlay, HJ; Jiang, J; Caringal, Y; Kover, A; Conder, ML; Xing, D; Levesque, P; Harper, T; Hsueh, MM; Atwal, K; Blanar, M; Wexler, R; Lloyd, J Triazolo and imidazo dihydropyrazolopyrimidine potassium channel antagonists. Bioorg Med Chem Lett23:1743-7 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 5 |
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| Name: | Potassium voltage-gated channel subfamily A member 5 |
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| Synonyms: | HK2 | HPCN1 | KCNA5 | KCNA5_HUMAN | Potassium voltage-gated channel subfamily A member 5 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.5 |
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| Type: | Enzyme |
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| Mol. Mass.: | 67222.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22460 |
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| Residue: | 613 |
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| Sequence: | MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
YALCLDTSRETDL
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| BDBM50430217 |
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| n/a |
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| Name | BDBM50430217 |
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| Synonyms: | CHEMBL2331989 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20Cl2N6 |
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| Mol. Mass. | 415.319 |
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| SMILES | CC1=Nc2ccnn2[C@@H](C1c1ncnn1C1CCCC1)c1ccc(Cl)c(Cl)c1 |r,t:1| |
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| Structure | 
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