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TargetSphingosine 1-phosphate receptor 3
LigandBDBM50027930
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1436859
EC50>10000±n/a nM
Citation Horan JCSanyal SChoi YHill-Drzewi MPatnaude LAnderson SFogal SMao CCook BNGueneva-Boucheva KFisher MBHickey EPack EBannen LCChan DSMac MBNg SMWang YXu WModis LKLemieux RM Piperazinyl-oxadiazoles as selective sphingosine-1-phosphate receptor agonists. Bioorg Med Chem Lett 24:4807-11 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 3
Name:Sphingosine 1-phosphate receptor Edg-5/Sphingosine 1-phosphate receptor Edg-3
Synonyms:EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:42278.13
Organism:Homo sapiens (Human)
Description:Q99500
Residue:378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV
LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV
ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH
NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA
LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL
ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP
SSCIMDKNAALQNGIFCN
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BDBM50027930
n/a
NameBDBM50027930
Synonyms:CHEMBL3344411
TypeSmall organic molecule
Emp. Form.C21H27ClFN5O4
Mol. Mass.467.922
SMILESN[C@H](CO)COc1cc(Cl)c(cc1F)-c1nc(no1)N1CCN(CC1)C(=O)C1CCCC1 |r|
Structure
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