| Reaction Details |
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 | Report a problem with these data |
| Target | Transthyretin |
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| Ligand | BDBM50030893 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1441631 (CHEMBL3377077) |
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| EC50 | 21000±n/a nM |
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| Citation |  Yokoyama, T; Kosaka, Y; Mizuguchi, M Inhibitory activities of propolis and its promising component, caffeic acid phenethyl ester, against amyloidogenesis of human transthyretin. J Med Chem57:8928-35 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transthyretin |
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| Name: | Transthyretin |
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| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 15884.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P02766 |
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| Residue: | 147 |
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| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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| BDBM50030893 |
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| n/a |
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| Name | BDBM50030893 |
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| Synonyms: | CHEBI:8393 | prenyl caffeate |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16O4 |
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| Mol. Mass. | 248.2744 |
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| SMILES | [#6]\[#6](-[#6])=[#6]\[#6]-[#8]-[#6](=O)\[#6]=[#6]\c1ccc(-[#8])c(-[#8])c1 |
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| Structure | 
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