| Reaction Details |
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 | Report a problem with these data |
| Target | Group 10 secretory phospholipase A2 |
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| Ligand | BDBM50031102 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1442449 (CHEMBL3380079) |
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| IC50 | 631±n/a nM |
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| Citation |  Chen, H; Knerr, L; Åkerud, T; Hallberg, K; Öster, L; Rohman, M; Österlund, K; Beisel, HG; Olsson, T; Brengdhal, J; Sandmark, J; Bodin, C Discovery of a novel pyrazole series of group X secreted phospholipase A2 inhibitor (sPLA2X) via fragment based virtual screening. Bioorg Med Chem Lett24:5251-5 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Group 10 secretory phospholipase A2 |
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| Name: | Group 10 secretory phospholipase A2 |
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| Synonyms: | Group X secretory phospholipase A2 | PA2GX_HUMAN | PLA2G10 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18153.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1442449 |
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| Residue: | 165 |
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| Sequence: | MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPI
AYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGP
AENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
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| BDBM50031102 |
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| n/a |
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| Name | BDBM50031102 |
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| Synonyms: | CHEMBL3337979 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H9N3OS |
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| Mol. Mass. | 207.252 |
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| SMILES | Cc1sccc1-c1cc(n[nH]1)C(N)=O |
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| Structure | 
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