| Reaction Details |
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 | Report a problem with these data |
| Target | Serine racemase |
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| Ligand | BDBM92990 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1441161 (CHEMBL3378825) |
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| IC50 | 400000±n/a nM |
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| Citation |  Vorlová, B; Nachtigallová, D; Jirásková-Vanícková, J; Ajani, H; Jansa, P; Rezác, J; Fanfrlík, J; Otyepka, M; Hobza, P; Konvalinka, J; Lep?ík, M Malonate-based inhibitors of mammalian serine racemase: kinetic characterization and structure-based computational study. Eur J Med Chem89:189-97 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine racemase |
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| Name: | Serine racemase |
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| Synonyms: | D-serine ammonia-lyase | D-serine dehydratase | L-serine ammonia-lyase | L-serine dehydratase | SRR_MOUSE | Srr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36355.92 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1441161 |
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| Residue: | 339 |
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| Sequence: | MCAQYCISFADVEKAHINIQDSIHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA
LNAIRGLIPDTPEEKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA
YGASIVYCDPSDESREKVTQRIMQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL
VVPVGGGGMVAGIAITIKALKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV
KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWGRMKLLIEPTAGVALAAVLSQHFQT
VSPEVKNVCIVLSGGNVDLTSLNWVGQAERPAPYQTVSV
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| BDBM92990 |
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| n/a |
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| Name | BDBM92990 |
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| Synonyms: | Aminomalonate |
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| Type | Small molecule |
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| Emp. Form. | C3H3NO4 |
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| Mol. Mass. | 117.0613 |
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| SMILES | NC(C([O-])=O)C([O-])=O |
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| Structure | 
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