Ki Summary

Reaction Details

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Target

KiSS-1 receptor

Ligand

BDBM50045512

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_1448386

0.087000±n/a nM

Citation

Asami T; Nishizawa N; Matsui H; Takatsu Y; Suzuki A; Kiba A; Terada M; Nishibori K; Nakayama M; Ban J; Matsumoto S; Tarui N; Ikeda Y; Yamaguchi M; Kusaka M; Ohtaki T; Kitada C Physicochemically and pharmacokinetically stable nonapeptide KISS1 receptor agonists with highly potent testosterone-suppressive activity. J Med Chem 57:6105-15 (2014) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

KiSS-1 receptor

Name:

KiSS-1 receptor

Synonyms:

n/a

Type:

PROTEIN

Mol. Mass.:

42915.37

Organism:

Rattus norvegicus

Description:

ChEMBL_1448383

Residue:

396

Sequence:

MAAEATLGPNVSWWAPSNASGCPGCGVNASDGPGSAPRPLDAWLVPLFFAALMLLGLVGN
SLVIFVICRHKHMQTVTNFYIANLAATDVTFLLCCVPFTALLYPLPTWVLGDFMCKFVNY
IQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALTVSLSIWVGSAAVSAPVLAL
HRLSPGPHTYCSEAFPSRALERAFALYNLLALYLLPLLATCACYGAMLRHLGRAAVRPAP
TDGALQGQLLAQRAGAVRTKVSRLVAAVVLLFAACWGPIQLFLVLQALGPSGAWHPRSYA
AYALKIWAHCMSYSNSALNPLLYAFLGSHFRQAFCRVCPCGPQRQRRPHASAHSDRAAPH
SVPHSRAAHPVRVRTPEPGNPVRRSPSVQDEHTAPL

BDBM50045512

n/a

Name

BDBM50045512

Synonyms:

CHEMBL3314229

Type

Small organic molecule

Emp. Form.

C62H82N16O13

Mol. Mass.

1259.4139

SMILES

CNC(=N)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|

Structure