| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1 |
|---|
| Ligand | BDBM50046751 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1452788 (CHEMBL3365130) |
|---|
| IC50 | 2000±n/a nM |
|---|
| Citation |  Kamal, A; Srinivasa Reddy, T; Polepalli, S; Paidakula, S; Srinivasulu, V; Ganga Reddy, V; Jain, N; Shankaraiah, N Synthesis and biological evaluation of 4-aza-2,3-dihydropyridophenanthrolines as tubulin polymerization inhibitors. Bioorg Med Chem Lett24:3356-60 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Similar to alpha-tubulin isoform 1 |
|---|
| Name: | Similar to alpha-tubulin isoform 1 |
|---|
| Synonyms: | Similar to alpha-tubulin isoform 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 10383.05 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_104716 |
|---|
| Residue: | 99 |
|---|
| Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
|
|
|
|---|
| BDBM50046751 |
|---|
| n/a |
|---|
| Name | BDBM50046751 |
|---|
| Synonyms: | CHEMBL3309646 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H19N3O4 |
|---|
| Mol. Mass. | 425.4361 |
|---|
| SMILES | COc1ccc(OC)c(c1)C1C2=C(COC2=O)Nc2c1c1cccnc1c1ncccc21 |t:12| |
|---|
| Structure | 
|
|---|
Search and Browse
