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TargetCannabinoid receptor 2
LigandBDBM50062496
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1462820
Ki>10000±n/a nM
Citation Bertini SParkkari TSavinainen JRArena CSaccomanni GSaguto SLigresti AAllarÓ MBruno AMarinelli LDi Marzo VNovellino EManera CMacchia M Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands. Eur J Med Chem 90:526-36 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 2
Name:Cannabinoid receptor 2
Synonyms:CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:39690.94
Organism:Homo sapiens (Human)
Description:P34972
Residue:360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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  Blast E-value cutoff:
BDBM50062496
n/a
NameBDBM50062496
Synonyms:CHEMBL3397446
TypeSmall organic molecule
Emp. Form.C23H29NO3
Mol. Mass.367.4813
SMILESCOc1ccc(cc1)-c1cc(C)c(OC)c(c1)C(=O)N[C@H]1CC[C@H](C)CC1 |r,wU:23.25,wD:20.21,(2.66,-2.78,;2.67,-1.54,;1.33,-.77,;1.33,.77,;,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;-2.67,1.54,;-2.67,3.08,;-4.01,3.85,;-4.01,5.08,;-5.34,3.08,;-6.68,3.84,;-7.74,3.22,;-5.34,1.54,;-4,.77,;-6.67,.76,;-7.74,1.37,;-6.66,-.78,;-7.99,-1.56,;-9.33,-.79,;-10.66,-1.56,;-10.66,-3.1,;-11.72,-3.72,;-9.32,-3.87,;-7.99,-3.1,)|
Structure
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