| Reaction Details |
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 | Report a problem with these data |
| Target | Hormone-sensitive lipase |
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| Ligand | BDBM50064412 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1464914 (CHEMBL3404384) |
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| IC50 | >100000±n/a nM |
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| Citation |  Vasilieva, E; Dutta, S; Malla, RK; Martin, BP; Spilling, CD; Dupureur, CM Rat hormone sensitive lipase inhibition by cyclipostins and their analogs. Bioorg Med Chem23:944-52 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hormone-sensitive lipase |
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| Name: | Hormone-sensitive lipase |
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| Synonyms: | Hormone-sensitive lipase | Hormone-sensitive lipase (HSL) | LIPS_RAT | Lipe |
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| Type: | Enzyme |
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| Mol. Mass.: | 116814.94 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P15304 |
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| Residue: | 1068 |
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| Sequence: | MKPRRPISFTREITAMEPSSTSVSRPEWRPEAQQTLTDYPGSRELQEFGIPQKQSLPNEA
TAQQGAEFQQEQGVQQSTLLQKLLTPLAFPVPQQSFPSHKVHSDQQEATSQNGPGAGKVH
TTQKELEHRDEHVGTAESGPAEPPPATEVEATSIAQAVSGPDKKLPTQTDLVSQERAEQS
DPTAQQTPLVQGVKSDQGSLIESGILARLQKLAIQQPSQEWKTFLDCVTESDMEKYLNSS
SKSNPPEPSGGTVIPGTLPSKQKPDCGKMSGYGGKLPHGKKGILQKHKHYWDTASAFSHS
MDLRTMTQSLVALAEDNMAFFSSQGPGETARRLSNVFAGVREQALGLEPTLGQLLGVAHH
FDLDTETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQ
LRALAYYAQRLLTINRPGVLFFEGDEGLSADFLQDYVTLHKGCFYGRCLGFQFTPAIRPF
LQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGAEFERIIQNLDVHFWKA
FWNITEIEVLSSLANMASTTVRVSRLLSLPPEAFEMPLTSDPKLTVTISPPLAHTGPGPV
LARLISYDLREGQDSKMLNSLAKSEGPRLELRPRPQQAPRSRALVVHIHGGGFVAQTSKS
HEPYLKNWAQELGVPIISIDYSLAPEAPFPRALEECFFAYCWAVKHCELLGSTGERICLA
GDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTTLQSSASPSRLLSLMDPLLPLSVLSK
CVSAYSGTETEDHFDSDQKALGVMGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPHKT
PLPATETLRPTDSGRLTESMRRSVSEAALAQPEGLLGTDSLKKLTIKDLSFKGNSEPSDS
PEMSQSMETLGPSTPSDVNFFLRSGNSQEEAETRDDISPMDGIPRVRAAFPDGFHPRRSS
QGVLHMPLYSSPIVKNPFMSPLLAPDVMLKTLPPVHLVACALDPMLDDSVMFARRLKDLG
QPVTLKVVEDLPHGFLSLAALCRETRQAAELCVQRIRLILTPPAAPLT
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| BDBM50064412 |
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| n/a |
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| Name | BDBM50064412 |
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| Synonyms: | CHEMBL3401169 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H43F2O5P |
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| Mol. Mass. | 480.5658 |
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| SMILES | CCCCCCCCCCCCCCCCOP1(=O)OC(C)=C(CCC1(F)F)C(=O)OC |c:21| |
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| Structure | 
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