| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Monoacylglycerol lipase ABHD6 |
|---|
| Ligand | BDBM50065645 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1464458 (CHEMBL3405400) |
|---|
| IC50 | 750±n/a nM |
|---|
| Citation |  Patel, JZ; Ahenkorah, S; Vaara, M; Staszewski, M; Adams, Y; Laitinen, T; Navia-Paldanius, D; Parkkari, T; Savinainen, JR; Walczynski, K; Laitinen, JT; Nevalainen, TJ Loratadine analogues as MAGL inhibitors. Bioorg Med Chem Lett25:1436-42 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Monoacylglycerol lipase ABHD6 |
|---|
| Name: | Monoacylglycerol lipase ABHD6 |
|---|
| Synonyms: | 2-arachidonoylglycerol hydrolase | ABHD6 | ABHD6_HUMAN | Abhydrolase domain-containing protein 6 | Monoacylglycerol lipase ABHD6 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38341.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_105457 |
|---|
| Residue: | 337 |
|---|
| Sequence: | MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQF
CYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLS
IDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYST
DNQFVQRLKELQGSAAVEKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHN
NFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANCQVEL
LENCGHSVVMERPRKTAKLIIDFLASVHNTDNNKKLD
|
|
|
|---|
| BDBM50065645 |
|---|
| n/a |
|---|
| Name | BDBM50065645 |
|---|
| Synonyms: | CHEMBL3402827 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H20N4O |
|---|
| Mol. Mass. | 368.4311 |
|---|
| SMILES | O=[#6](-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-[#6]=[#6]-c2ccccc-12)-n1cncn1 |c:17| |
|---|
| Structure | 
|
|---|
Search and Browse
