| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Aldehyde dehydrogenase family 1 member A3 |
|---|
| Ligand | BDBM50076551 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1473079 (CHEMBL3421189) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Morgan, CA; Hurley, TD Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors. J Med Chem58:1964-75 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Aldehyde dehydrogenase family 1 member A3 |
|---|
| Name: | Aldehyde dehydrogenase family 1 member A3 |
|---|
| Synonyms: | AL1A3_HUMAN | ALDH1A3 | ALDH6 | Aldehyde dehydrogenase 6 | Aldehyde dehydrogenase family 1 member A3 | RALDH-3 | RalDH3 | Retinaldehyde dehydrogenase 3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56110.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_109700 |
|---|
| Residue: | 512 |
|---|
| Sequence: | MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQI
CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM
DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPW
NFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTV
GAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVE
CAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQK
QFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPIL
KFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGF
KMSGNGRELGEYALAEYTEVKTVTIKLGDKNP
|
|
|
|---|
| BDBM50076551 |
|---|
| n/a |
|---|
| Name | BDBM50076551 |
|---|
| Synonyms: | CHEMBL3416555 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H31N5O2 |
|---|
| Mol. Mass. | 361.4817 |
|---|
| SMILES | CC(C)CCn1c(CN2CCC(C)CC2)nc2n(C)c(=O)n(C)c(=O)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
