| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50078770 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1472323 (CHEMBL3419673) |
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| Ki | 4.4±n/a nM |
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| Citation |  Ogawa, G; Tius, MA; Zhou, H; Nikas, SP; Halikhedkar, A; Mallipeddi, S; Makriyannis, A 3'-functionalized adamantyl cannabinoid receptor probes. J Med Chem58:3104-16 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50078770 |
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| n/a |
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| Name | BDBM50078770 |
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| Synonyms: | CHEMBL3416129 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H35N3O3 |
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| Mol. Mass. | 437.5744 |
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| SMILES | [H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)[C@]12CC3CC(C[C@@](CN=[N+]=[N-])(C3)C1)C2 |r,THB:23:22:33.24.25:32,25:24:21:26.32.31,25:26:21:33.24.23,27:26:21:33.24.23| |
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| Structure | 
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