| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50083544 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1474462 (CHEMBL3423751) |
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| Kd | 11000±n/a nM |
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| Citation |  Molero, A; Vendrell, M; Bonaventura, J; Zachmann, J; López, L; Pardo, L; Lluis, C; Cortés, A; Albericio, F; Casadó, V; Royo, M A solid-phase combinatorial approach for indoloquinolizidine-peptides with high affinity at D(1) and D(2) dopamine receptors. Eur J Med Chem97:173-80 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50083544 |
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| n/a |
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| Name | BDBM50083544 |
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| Synonyms: | CHEMBL3423409 |
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| Type | Small organic molecule |
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| Emp. Form. | C43H61FN8O5 |
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| Mol. Mass. | 788.9934 |
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| SMILES | [H][C@]12CC[C@@H](CN1CCc1c2[nH]c2ccccc12)C(=O)NCCCCCC(=O)N[C@@H](CCCC)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| |
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| Structure | 
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