| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
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| Ligand | BDBM50088567 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1495689 (CHEMBL3578677) |
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| IC50 | 62.0±n/a nM |
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| Citation |  El-Faham, A; Zainab Al Marhoon, na; Abdel-Megeed, A; Khattab, SN; Bekhit, AA; Albericio, F a-Ketoamino acid ester derivatives as promising MAO inhibitors. Bioorg Med Chem Lett25:70-4 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] A |
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| Name: | Amine oxidase [flavin-containing] A |
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| Synonyms: | AOFA_RAT | Amine oxidase (flavin-containing) A | Amine oxidase [flavin-containing] A | Maoa | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A (MAO-A) | Monoamine oxidase A (rMAO-A) | Monoamine oxidase type A (MAOA) |
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| Type: | Enzyme |
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| Mol. Mass.: | 59515.21 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 526 |
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| Sequence: | MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHV
KWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLA
YLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNI
NVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKL
SSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPM
GAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADR
QAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKD
VPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
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| BDBM50088567 |
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| n/a |
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| Name | BDBM50088567 |
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| Synonyms: | CHEMBL3577038 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N2O5 |
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| Mol. Mass. | 306.3138 |
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| SMILES | COC(=O)CCCNC(=O)C(=O)c1ccccc1NC(C)=O |
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| Structure | 
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