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TargetAmine oxidase [flavin-containing] B
LigandBDBM15581
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1495690 (CHEMBL3578678)
IC50 98000±n/a nM
Citation El-Faham, A; Zainab Al Marhoon, na; Abdel-Megeed, A; Khattab, SN; Bekhit, AA; Albericio, F a-Ketoamino acid ester derivatives as promising MAO inhibitors. Bioorg Med Chem Lett25:70-4 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:AOFB_BOVIN | Amine oxidase [flavin-containing] B | MAO-B | MAOB | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B | Monoamine oxidase type B
Type:PROTEIN
Mol. Mass.:58428.94
Organism:Bos taurus
Description:ChEMBL_1501478
Residue:520
Sequence:
MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWR
TMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEV
SALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQ
TGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVY
YKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEER
LKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTT
FLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
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BDBM15581
n/a
NameBDBM15581
Synonyms:CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine | US8633208, Clorgyline | US9603833, Clorgyline | [3-(2,4-dichlorophenoxy)propyl](methyl)prop-2-yn-1-ylamine
TypeSmall organic molecule
Emp. Form.C13H15Cl2NO
Mol. Mass.272.17
SMILESCN(CCCOc1ccc(Cl)cc1Cl)CC#C
Structure
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