| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase N catalytic chain |
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| Ligand | BDBM50089686 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1496379 (CHEMBL3580145) |
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| IC50 | 5700±n/a nM |
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| Citation |  Halland, N; Brönstrup, M; Czech, J; Czechtizky, W; Evers, A; Follmann, M; Kohlmann, M; Schiell, M; Kurz, M; Schreuder, HA; Kallus, C Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa) from Natural Product Anabaenopeptin. J Med Chem58:4839-44 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase N catalytic chain |
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| Name: | Carboxypeptidase N catalytic chain |
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| Synonyms: | ACBP | Anaphylatoxin inactivator | Arginine carboxypeptidase | CBPN_HUMAN | CPN | CPN1 | Carboxypeptidase N catalytic chain | Carboxypeptidase N polypeptide 1 | Carboxypeptidase N small subunit | Carboxypeptidase N, catalytic subunit | Kininase-1 | Lysine carboxypeptidase | Plasma carboxypeptidase B | SCPN | Serum carboxypeptidase N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52293.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1496379 |
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| Residue: | 458 |
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| Sequence: | MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL
YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD
TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN
HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT
ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT
NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS
VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP
QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
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| BDBM50089686 |
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| n/a |
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| Name | BDBM50089686 |
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| Synonyms: | CHEMBL3577334 |
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| Type | Small organic molecule |
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| Emp. Form. | C41H60N8O9 |
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| Mol. Mass. | 808.9633 |
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| SMILES | CC(C)[C@@H]1NC(=O)[C@@H](CCCCNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)N(C)C(=O)[C@H](CCc2ccc(O)cc2)NC1=O)NC(=O)N[C@@H](CCCCN)C(O)=O |r| |
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| Structure | 
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