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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Alpha-1B adrenergic receptor | ||
| Ligand | BDBM50091349 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1497771 (CHEMBL3583291) | ||
| Ki | 7.3±n/a nM | ||
| Citation |  Zhang, W; Ma, Z; Li, W; Li, G; Chen, L; Liu, Z; Du, L; Li, M Discovery of Quinazoline-Based Fluorescent Probes toa1-Adrenergic Receptors. ACS Med Chem Lett6:502-6 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Alpha-1B adrenergic receptor | |||
| Name: | Alpha-1B adrenergic receptor | ||
| Synonyms: | ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 56862.13 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P35368 | ||
| Residue: | 520 | ||
| Sequence: |
| ||
| BDBM50091349 | |||
| n/a | |||
| Name | BDBM50091349 | ||
| Synonyms: | CHEMBL3582271 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C35H30N6O7S | ||
| Mol. Mass. | 678.714 | ||
| SMILES | COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=S)Nc1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12 |(6.4,-19.42,;5.33,-20.04,;4,-19.27,;3.99,-17.71,;2.66,-16.94,;2.67,-15.4,;1.34,-14.63,;.01,-15.4,;0,-16.94,;-1.07,-17.55,;1.33,-17.71,;1.33,-19.24,;2.67,-20.03,;2.66,-21.57,;1.59,-22.18,;1.34,-13.09,;.01,-12.32,;.01,-10.78,;1.34,-10.01,;2.67,-10.78,;2.67,-12.32,;1.34,-8.47,;2.41,-7.85,;0,-7.7,;0,-6.16,;-1.33,-5.39,;-1.33,-3.85,;0,-3.08,;1.34,-3.85,;1.34,-5.39,;2.67,-3.09,;2.68,-2.06,;3.74,-3.7,;,-1.54,;1.31,-.77,;2.67,-1.54,;4,-.77,;4,.77,;5.07,1.39,;2.67,1.54,;1.31,.77,;,1.54,;-1.33,.77,;-2.67,1.54,;-4,.77,;-5.07,1.39,;-4,-.77,;-2.67,-1.54,;-1.33,-.77,)| | ||
| Structure | 
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