| Reaction Details |
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 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1/Tubulin beta-2B chain |
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| Ligand | BDBM50098800 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1504929 (CHEMBL3595578) |
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| IC50 | 4900±n/a nM |
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| Citation |  Lee, HY; Chang, CY; Lai, MJ; Chuang, HY; Kuo, CC; Chang, CY; Chang, JY; Liou, JP Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes. Bioorg Med Chem23:4230-6 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Similar to alpha-tubulin isoform 1/Tubulin beta-2B chain |
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| Name: | Similar to alpha-tubulin isoform 1/Tubulin beta-2B chain |
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| Synonyms: | Tubulin | Tubulin alpha chain /beta chain |
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| Type: | n/a |
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| Mol. Mass.: | n/a |
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| Description: | ASSAY_ID of EBI is 51441 |
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| Components: | This complex has 2 components. |
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| Component 1 |
| Name: | Tubulin beta-2B chain |
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| Synonyms: | TBB2B_BOVIN | TUBB2B | Tubulin | Tubulin beta chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49932.38 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_211651 |
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| Residue: | 445 |
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| Sequence: | MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATADEQGEFEEEEGEDEA
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| Component 2 |
| Name: | Similar to alpha-tubulin isoform 1 |
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| Synonyms: | Tubulin |
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| Type: | PROTEIN |
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| Mol. Mass.: | 9422.48 |
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| Organism: | Bos taurus |
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| Description: | EBI_18002 |
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| Residue: | 84 |
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| Sequence: | PSPQVSTAVVEPYNSILTTKHLEHSDCFMVDNEAIYDICRRNLDIERPTTRNLNRLMSQI
VSSITASLRFDGALTVDLTDVQTS
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| BDBM50098800 |
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| n/a |
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| Name | BDBM50098800 |
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| Synonyms: | CHEMBL3593872 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19NO5 |
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| Mol. Mass. | 341.3579 |
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| SMILES | COc1cc(C(=O)c2ccc3n(C)ccc3c2)c(O)c(OC)c1OC |
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| Structure | 
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