| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50103558 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1434153 (CHEMBL3383390) |
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| EC50 | 216±n/a nM |
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| Citation |  Scott, JS; Bowker, SS; Brocklehurst, KJ; Brown, HS; Clarke, DS; Easter, A; Ertan, A; Goldberg, K; Hudson, JA; Kavanagh, S; Laber, D; Leach, AG; MacFaul, PA; Martin, EA; McKerrecher, D; Schofield, P; Svensson, PH; Teague, J Circumventing seizure activity in a series of G protein coupled receptor 119 (GPR119) agonists. J Med Chem57:8984-98 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | GP119_MOUSE | Gpr119 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37009.07 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1506420 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISG
LVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGL
VAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLL
FVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSP
FLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKF
FTSILLLLPARNRGPERTRESAYHIVTISHPELDG
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| BDBM50103558 |
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| n/a |
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| Name | BDBM50103558 |
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| Synonyms: | CHEMBL3357999 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17F4N7O2 |
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| Mol. Mass. | 463.3883 |
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| SMILES | C[C@@H]1CN(CCN1c1ncc(OCc2ccc(cc2F)C#N)cn1)c1nnc(o1)C(F)(F)F |r| |
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| Structure | 
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