| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
|---|
| Ligand | BDBM50103562 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1434151 (CHEMBL3383388) |
|---|
| EC50 | 55±n/a nM |
|---|
| Citation |  Scott, JS; Bowker, SS; Brocklehurst, KJ; Brown, HS; Clarke, DS; Easter, A; Ertan, A; Goldberg, K; Hudson, JA; Kavanagh, S; Laber, D; Leach, AG; MacFaul, PA; Martin, EA; McKerrecher, D; Schofield, P; Svensson, PH; Teague, J Circumventing seizure activity in a series of G protein coupled receptor 119 (GPR119) agonists. J Med Chem57:8984-98 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucose-dependent insulinotropic receptor |
|---|
| Name: | Glucose-dependent insulinotropic receptor |
|---|
| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 36901.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8TDV5 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
|
|
|
|---|
| BDBM50103562 |
|---|
| n/a |
|---|
| Name | BDBM50103562 |
|---|
| Synonyms: | CHEMBL3357995 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H20F3N7O4S |
|---|
| Mol. Mass. | 523.488 |
|---|
| SMILES | C[C@@H]1CN(CCN1c1ncc(OCc2ccc(cc2C#N)S(C)(=O)=O)cn1)c1nnc(o1)C(F)(F)F |r| |
|---|
| Structure | 
|
|---|
Search and Browse
