| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-synuclein |
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| Ligand | BDBM50103964 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1505263 (CHEMBL3594888) |
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| Kd | 8.9±n/a nM |
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| Citation |  Chu, W; Zhou, D; Gaba, V; Liu, J; Li, S; Peng, X; Xu, J; Dhavale, D; Bagchi, DP; d'Avignon, A; Shakerdge, NB; Bacskai, BJ; Tu, Z; Kotzbauer, PT; Mach, RH Design, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands fora-Synuclein Fibrils. J Med Chem58:6002-17 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-synuclein |
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| Name: | Alpha-synuclein |
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| Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 14451.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37840 |
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| Residue: | 140 |
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| Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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| BDBM50103964 |
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| n/a |
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| Name | BDBM50103964 |
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| Synonyms: | CHEMBL3593932 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H21FN2O4 |
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| Mol. Mass. | 444.4543 |
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| SMILES | [O-][N+](=O)c1ccc(\C=C\C=C2/C(=O)N(Cc3ccc(OCCF)cc3)c3ccccc23)cc1 |
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| Structure | 
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