| Reaction Details |
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 | Report a problem with these data |
| Target | Lysosomal alpha-glucosidase |
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| Ligand | BDBM50104671 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1506060 (CHEMBL3595864) |
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| IC50 | 2200±n/a nM |
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| Citation |  Liu, Y; Yang, Q; Xia, G; Huang, H; Li, H; Ma, L; Lu, Y; He, L; Xia, X; She, Z Polyketides witha-Glucosidase Inhibitory Activity from a Mangrove Endophytic Fungus, Penicillium sp. HN29-3B1. J Nat Prod78:1816-22 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysosomal alpha-glucosidase |
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| Name: | Lysosomal alpha-glucosidase |
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| Synonyms: | 70 kDa lysosomal alpha-glucosidase | 76 kDa lysosomal alpha-glucosidase | Acid maltase | Aglucosidase alfa | Alpha glucosidase | GAA | LYAG_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 105312.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1506060 |
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| Residue: | 952 |
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| Sequence: | MGVRHPPCSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGA
SRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGA
QMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLH
FTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLF
FADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLA
LEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGY
PFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDG
FRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKV
WPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELEN
PPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISR
STFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVR
WTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAG
ETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPV
EALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQP
MALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQ
LQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC
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| BDBM50104671 |
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| n/a |
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| Name | BDBM50104671 |
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| Synonyms: | CHEMBL3593568 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12O4 |
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| Mol. Mass. | 232.232 |
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| SMILES | Cc1cc(O)c(O)cc1-c1cc(O)cc(O)c1 |
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| Structure | 
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