| Reaction Details |
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 | Report a problem with these data |
| Target | Thyrotropin-releasing hormone receptor |
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| Ligand | BDBM50109039 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1508580 (CHEMBL3602663) |
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| IC50 | >50000±n/a nM |
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| Citation |  Meena, CL; Thakur, A; Nandekar, PP; Sangamwar, AT; Sharma, SS; Jain, R Synthesis of CNS active thyrotropin-releasing hormone (TRH)-like peptides: Biological evaluation and effect on cognitive impairment induced by cerebral ischemia in mice. Bioorg Med Chem23:5641-53 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thyrotropin-releasing hormone receptor |
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| Name: | Thyrotropin-releasing hormone receptor |
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| Synonyms: | TRH-R2 | Thyrotropin-releasing hormone receptor 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27545.04 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_109850 |
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| Residue: | 251 |
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| Sequence: | MDGPSNVSLVHGDTTLGLPEYKVVSVLLVLLVCTVGIVGNAMVVLVVLTSRDMHTPTNCY
LVSLALADLIVLLAAGLPNVSDSLVGHWIYGHAGCLGITYFQYLGINVSSCSILAFTVER
YIAICHPMRAQTVCTVARARRIIAGIWGVTSLYCLLWFFLVDLNVRDNQRLECGYKVSRG
LYLPIYLLDFAVFFIAPLLGTLVLYGFIGRILFQSPLSQEAWQKERQSHGQSEGTPGNCS
RSKSSMSSRKQ
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| BDBM50109039 |
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| n/a |
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| Name | BDBM50109039 |
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| Synonyms: | CHEMBL3600454 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19Br2N7O3 |
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| Mol. Mass. | 529.186 |
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| SMILES | Cc1cnc(cn1)C(=O)N[C@@H](Cc1nc(Br)[nH]c1Br)C(=O)N1CCC[C@H]1C(N)=O |r| |
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| Structure | 
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