| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 6 |
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| Ligand | BDBM50114076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1511151 (CHEMBL3607668) |
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| IC50 | 112000±n/a nM |
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| Citation |  Meltzer, D; Ethan, O; Arguin, G; Nadel, Y; Danino, O; Lecka, J; Sévigny, J; Gendron, FP; Fischer, B Synthesis and structure-activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists. Bioorg Med Chem23:5764-73 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 6 |
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| Name: | P2Y purinoceptor 6 |
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| Synonyms: | P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36452.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1511151 |
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| Residue: | 328 |
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| Sequence: | MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTR
TAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCI
SFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDL
SPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARM
AVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPIL
FYFTQKKFRRRPHELLQKLTAKWQRQGR
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| BDBM50114076 |
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| n/a |
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| Name | BDBM50114076 |
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| Synonyms: | CHEMBL3604024 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H11N2Na2O12PS |
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| Mol. Mass. | 448.208 |
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| SMILES | [Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OS([O-])(=O)=O)n1ccc(=O)[nH]c1=O |r| |
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| Structure | 
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