| Reaction Details |
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 | Report a problem with these data |
| Target | B2 bradykinin receptor |
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| Ligand | BDBM50121684 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1516519 (CHEMBL3619870) |
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| Ki | 9000±n/a nM |
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| Citation |  Deekonda, S; Rankin, D; Davis, P; Lai, J; Porreca, F; Hruby, VJ Design, synthesis and biological evaluation of multifunctional ligands targeting opioid and bradykinin 2 receptors. Bioorg Med Chem Lett25:4148-52 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B2 bradykinin receptor |
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| Name: | B2 bradykinin receptor |
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| Synonyms: | B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44467.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | B2 BRADYKININ BDKRB2 HUMAN::P30411 |
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| Residue: | 391 |
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| Sequence: | MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
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| BDBM50121684 |
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| n/a |
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| Name | BDBM50121684 |
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| Synonyms: | CHEMBL3616944 |
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| Type | Small organic molecule |
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| Emp. Form. | C59H89N19O13S |
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| Mol. Mass. | 1304.522 |
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| SMILES | N[C@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CC(O)CC1C(=O)NCC(=O)NC(Cc1cccs1)C(=O)N[C@@H](CO)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)N1C2CCCCC2CC1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| |
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| Structure | 
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