| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neurotensin receptor type 1 |
|---|
| Ligand | BDBM50048908 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1520149 (CHEMBL3625721) |
|---|
| EC50 | 1.3±n/a nM |
|---|
| Citation |  Fanelli, R; Besserer-Offroy, É; René, A; Côté, J; Tétreault, P; Collerette-Tremblay, J; Longpré, JM; Leduc, R; Martinez, J; Sarret, P; Cavelier, F Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues. J Med Chem58:7785-95 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neurotensin receptor type 1 |
|---|
| Name: | Neurotensin receptor type 1 |
|---|
| Synonyms: | NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 47070.64 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1466612 |
|---|
| Residue: | 424 |
|---|
| Sequence: | MHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTD
IYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLA
MPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTL
MSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQV
NTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRV
QALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYV
SSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATR
ETLY
|
|
|
|---|
| BDBM50048908 |
|---|
| n/a |
|---|
| Name | BDBM50048908 |
|---|
| Synonyms: | CHEMBL415788 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C38H64N12O8 |
|---|
| Mol. Mass. | 816.9904 |
|---|
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
