| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50128834 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1522861 (CHEMBL3630579) |
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| EC50 | 14±n/a nM |
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| Citation |  Jones, LH; Burrows, J; Feeder, N; Glossop, P; James, K; Jones, RM; Kenyon, AS; Patel, S; Roberts, DF; Selby, MD; Strang, RS; Stuart, EF; Trevethick, MA; Watson, J; Wright, KN; Clarke, N Molecular hybridization yields triazole bronchodilators for the treatment of COPD. Bioorg Med Chem Lett25:5121-6 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50128834 |
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| n/a |
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| Name | BDBM50128834 |
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| Synonyms: | CHEMBL3629359 |
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| Type | Small organic molecule |
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| Emp. Form. | C41H58N6O4 |
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| Mol. Mass. | 698.937 |
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| SMILES | O[C@@H](CNCCCCCCCCCN1CCC(Cn2cnc(n2)[C@@](O)(C2CCCCC2)c2ccccc2)CC1)c1ccc(O)c2[nH]c(=O)ccc12 |r| |
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| Structure | 
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