| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-2 |
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| Ligand | BDBM50131373 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1526829 |
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| Ki | 1.7±n/a nM |
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| Citation |  Hu, H; Wang, X; Chan, GK; Chang, JH; Do, S; Drummond, J; Ebens, A; Lee, W; Ly, J; Lyssikatos, JP; Murray, J; Moffat, JG; Chao, Q; Tsui, V; Wallweber, H; Kolesnikov, A Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors. Bioorg Med Chem Lett25:5258-64 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-2 |
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| Name: | Serine/threonine-protein kinase pim-2 |
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| Synonyms: | PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2) |
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| Type: | Serine/threonine-protein kinase |
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| Mol. Mass.: | 34185.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9P1W9 |
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| Residue: | 311 |
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| Sequence: | MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
GPAPLAWSLLP
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| BDBM50131373 |
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| n/a |
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| Name | BDBM50131373 |
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| Synonyms: | CHEMBL3634777 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20FN5O |
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| Mol. Mass. | 389.4255 |
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| SMILES | Fc1ccccc1-c1n[nH]c2cnc(cc12)-c1cnccc1O[C@@H]1CCCNC1 |r| |
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| Structure | 
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