| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase, alpha family |
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| Ligand | BDBM10873 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1543854 (CHEMBL3749744) |
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| Ki | 92±n/a nM |
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| Citation |  Vullo, D; Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT Sulfonamide inhibition studies of thea-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. Bioorg Med Chem Lett26:401-5 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase, alpha family |
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| Name: | Carbonic anhydrase, alpha family |
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| Synonyms: | Carbonic anhydrase, alpha family |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35831.01 |
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| Organism: | Thiomicrospira crunogena (strain XCL-2) |
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| Description: | ChEMBL_109899 |
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| Residue: | 315 |
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| Sequence: | MKKRFSFIFIFLVALPLYSANNVAAPLIDLGAEAKKQAQKSAATQSAVPEKESATKVAEK
QKEPEEKAKPEPKKPPHWGYFGEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTS
LPGFDVYYRETALKLINNGHTLQVNIPLGSYIKINGHRYELLQYHFHTPSEHQRDGFNYP
MEMHLVHKDGDGNLAVIAILFQEGEENETLAKLMSFLPQTLKKQEIHESVKIHPAKFFPA
DKKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYLGSNARPVQRQNARTLLK
SWPDRNRANTVYEFY
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| BDBM10873 |
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| n/a |
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| Name | BDBM10873 |
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| Synonyms: | 4-[(2-aminopyrimidin-4-yl)amino]benzene-1-sulfonamide | CHEMBL6633 | US9616064, Compound 1aa | aromatic/heteroaromatic sulfonamide 18 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H11N5O2S |
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| Mol. Mass. | 265.292 |
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| SMILES | Nc1nccc(Nc2ccc(cc2)S(N)(=O)=O)n1 |
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| Structure | 
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