| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase, alpha family |
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| Ligand | BDBM4703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1543854 (CHEMBL3749744) |
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| Ki | 85±n/a nM |
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| Citation |  Vullo, D; Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT Sulfonamide inhibition studies of thea-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. Bioorg Med Chem Lett26:401-5 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase, alpha family |
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| Name: | Carbonic anhydrase, alpha family |
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| Synonyms: | Carbonic anhydrase, alpha family |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35831.01 |
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| Organism: | Thiomicrospira crunogena (strain XCL-2) |
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| Description: | ChEMBL_109899 |
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| Residue: | 315 |
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| Sequence: | MKKRFSFIFIFLVALPLYSANNVAAPLIDLGAEAKKQAQKSAATQSAVPEKESATKVAEK
QKEPEEKAKPEPKKPPHWGYFGEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTS
LPGFDVYYRETALKLINNGHTLQVNIPLGSYIKINGHRYELLQYHFHTPSEHQRDGFNYP
MEMHLVHKDGDGNLAVIAILFQEGEENETLAKLMSFLPQTLKKQEIHESVKIHPAKFFPA
DKKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYLGSNARPVQRQNARTLLK
SWPDRNRANTVYEFY
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| BDBM4703 |
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| n/a |
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| Name | BDBM4703 |
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| Synonyms: | 4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic acid | Benzoic Acid deriv. 31 | CHEMBL414 | JMC522226 Compound 22 | JMC523116 Compound 22 | JMC52646 Compound 23 | aromatic/heteroaromatic sulfonamide 23 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H7NO4S |
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| Mol. Mass. | 201.2 |
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| SMILES | NS(=O)(=O)c1ccc(cc1)C(O)=O |
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| Structure | 
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